Document Type
Article
Publication Date
5-25-2023
Abstract
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is performed to treat biliary complications after a liver transplantation; however, the previously available literature on the safety of ERCP in liver transplant patients is limited. We aimed to study the safety of ERCP in liver transplant patients.
METHODS: We used a National Inpatient Sample database from 2016-2019 to identify patients who underwent ERCP and had a history of a liver transplantation, using the international classification of diseases, 10
RESULTS: Liver transplant patients who underwent ERCP had a higher rate of post-ERCP pancreatitis and bleeding compared to the general adult population (11.39% vs. 9.19%, 0.83% vs. 0.53%, respectively). However, the adjusted odds of post-ERCP pancreatitis (adjusted odds ratio [aOR] 1.13, 95% confidence interval [CI] 0.86-1.49; P=0.36) and bleeding (aOR 1.41, 95%CI 0.58-3.46; P=0.45) were similar in both the liver transplant and no-transplant groups. There was no difference in the odds of post-ERCP cholangitis (aOR 1.26, 95%CI 0.80-2.01; P=0.32), and sepsis (aOR 0.94, 95%CI 0.66-1.34; P=0.76) between liver transplant and no transplant groups. Biliary stricture was the most common indication for ERCP in the liver transplant group, whereas choledocholithiasis was the main reason for ERCP in the general adult population.
CONCLUSIONS: ERCP is a safe procedure for treating biliary complications in liver transplant patients. The odds of post-ERCP complications (pancreatitis, bleeding, sepsis, cholangitis) in liver transplant patients are comparable to those in patients with no transplantation.
Recommended Citation
Tarar, Zahid Ijaz; Farooq, Umer; Gandhi, Mustafa; Zafar, Muhammad Usman; Saleem, Saad; and Kamal, Faisal, "Safety and Indications for Endoscopic Retrograde Cholangiopancreatography in Liver Transplant Patients: An Analysis of the United States’ National Inpatient Sample Database" (2023). Division of Gastroenterology and Hepatology Faculty Papers. Paper 90.
https://jdc.jefferson.edu/gastro_hepfp/90
Creative Commons License
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PubMed ID
37396010
Language
English
Comments
This article is the author's final published version in Annals of Gastroenterology, Volume 36, 2023, Pg. 1 - 7.
The published version is available at https://doi.org/10.20524/aog.2023.0801. Copyright © 2023 Hellenic Society of Gastroenterology.