Document Type
Article
Publication Date
7-13-2026
Abstract
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by recurrent abdominal pain and changes in bowel habits without measurable disease processes. Recent research emphasizes the gut-brain-microbiome (GBM) axis and explores how microbiota influence gastrointestinal and central nervous system functions. Here, we first discuss a brief overview of various treatment approaches for IBS, focusing on interventions such as probiotics, prebiotics, or synbiotics that target the GBM axis in adults with IBS. Relevant trials discussed the use of probiotics, prebiotics, or synbiotics.
Recommended Citation
Wodarczyk, Gina; Winte, Maria; Mastellone, Diana; Singh, Termen; DeSipio, Joshua; and Phadtare, Sangita, "Biotic Therapies for Irritable Bowel Syndrome: Current Interventions" (2026). Division of Gastroenterology and Hepatology Faculty Papers. Paper 135.
https://jdc.jefferson.edu/gastro_hepfp/135
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
42445725
Language
English

Comments
This article is the author’s final published version in Gastroenterology Report, Volume 14, 2026, Article number goag062.
The published version is available at https://doi.org/10.1093/gastro/goag062. Copyright © The Author(s) 2026.