Poster presented at: Digestive Disease Week (DDW) International meeting in San Diego, California.
Background and Aims:
Rectoanal incontinence is associated with defective Internal Anal Sphincter (IAS). Current therapies are not satisfactory, raising a potential for the replacement of the dysfunctional IAS with the reconstructs. Present studies were performed to develop human IAS smooth muscle reconstructs with functional and molecular attributes similar to the intact human IAS Smooth muscle (SM).
Recommended CitationSingh, Jagmohan and Rattan, Satish, "Development of Myogenic IAS Reconstructs from Human Internal Anal Sphincter (IAS) Smooth Muscle Cells (SMCs) with Functional and Molecular Properties Similar to Intact Human IAS" (2012). Division of Gastroenterology and Hepatology Faculty Papers. Paper 10.