Validation of a Novel, Non-Invasive System for Autonomic Profiling in Healthy Volunteers

Authors

Agostino Ingraldi, Thomas Jefferson UniversityFollow
Behzad B. Pavri, Thomas Jefferson UniversityFollow
Himanshu Patel, Thomas Jefferson UniversityFollow
Sammy Zakaria, Thomas Jefferson UniversityFollow
Reginald T. Ho, Thomas Jefferson UniversityFollow
Arnold J. Greenspon, Thomas Jefferson UniversityFollow

Abstract

Noninvasive profiling of the autonomic nervous system has been shown to have prognostic value in patients with myocardial infarction, CHF and diabetes. The ANSAR system (ANX 3.0, Philadelphia, PA) is a new commercially available system that utilizes respiratory rate, HR and BP to assess on-going sympathovagal modulation during various maneuvers known to evoke autonomic perturbations. Instead of using conventional Fast Fourier Transform for frequency domain analysis, a Continuous Wavelet Transform (CWT) is used to generate numerical and graphical data. The system calculates Low Frequency Area (LFA, analogous to LF Power) and Respiratory Frequency Area (RFA, analogous to High Frequency Power.) A time domain index (pNN50 is also calculated.

Recommended Citation

Ingraldi, Agostino; Pavri, Behzad B.; Patel, Himanshu; Zakaria, Sammy; Ho, Reginald T.; and Greenspon, Arnold J. (2003) "Validation of a Novel, Non-Invasive System for Autonomic Profiling in Healthy Volunteers," The Medicine Forum: Vol. 4, Article 11.
DOI: https://doi.org/10.29046/TMF.004.1.003
Available at: https://jdc.jefferson.edu/tmf/vol4/iss1/11