Amphetamines are a well-established cause of liver injury though the typical presentation is that of illicit drug abuse rather than liver injury occurring in a prescribed setting.1 Lisdexamfetamine (Vyvanse) is one of the most commonly prescribed stimulant medications used for the treatment of Attention Deficit Hyperactive Disorder (ADHD). The authors were only able to find a single case of lisdexamfetamine-related drug-induced liver injury (DILI) occurring in the pediatric population in their review of the literature. Here we present a case of suspected lisdexamfetamine DILI in an adult patient.
Kishfy, MD, Louis; Bilello, MD, Justin; Ahmed, MD, Monjur; and Flerova, MD, Elizaveta
"A Case of Suspected Lisdexamfetamine (Vyvanse) Drug-Induced Liver Injury,"
The Medicine Forum: Vol. 24, Article 12.
Available at: https://jdc.jefferson.edu/tmf/vol24/iss1/12