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Notes from the lectures of Jacob Mendes Da Costa taken by 1887 graduate of Jefferson Medical College William W. H. Wehner. Jacob Mendes Da Costa served in the U.S. Army during the American Civil War and undertook research on "irritable heart" (neurocirculatory asthenia) in soldiers, research that was of landmark importance in clinical medicine. After the Civil War, Da Costa continued his teaching at the Pennsylvania Hospital (1865-1900). He began at Jefferson Medical College as a lecturer on clinical medicine (1866-1872), then professor of theory and practice of medicine (1872-1891), and finally professor emeritus (1891-1900). While Da Costa retired in 1891, he continued his medical efforts as a consultant and supporter for medical education reform and served as a trustee of the University of Pennsylvania in 1899 (University Archives and Special Collections). Notes in this book include Da Costa's lectures on typhoid, malaria, yellow fever, small pox, and a host of other diseases. 179 pages.


University Archives and Special Collections of Thomas Jefferson University. 10 Notable Jefferson Alumni of the Past: Jacob Mendes Da Costa. Retrieved from:

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Jefferson Medical College, Jacob Mendes Da Costa, Scarlet Fever, Typhoid Fever, Yellow Fever, Smallpox, Tuberculosis, Pneumonia




Bacterial Infections and Mycoses | Cardiovascular Diseases | History of Science, Technology, and Medicine | Pathological Conditions, Signs and Symptoms | Virus Diseases

Notes on Practice of Medicine, from Prof. Da Costa's Lectures, at The Jefferson Medical College, During Sessions of [18]84-85 and [18]85-86



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