Document Type

Article

Publication Date

11-1-2025

Comments

This article is the author's final published version in JAAD Case Reports, Volume 65, November 2025, Pages 12-14.

The published version is available at https://doi.org/10.1016/j.jdcr.2025.08.007. Copyright © 2025 The Author(s).

Abstract

Introduction

Porokeratosis encompasses a group of skin disorders characterized by abnormal keratinization, with the defining histologic feature of cornoid lamellae, which are stacks of parakeratotic cells that overlie dyskeratotic keratinocytes. Several subtypes of porokeratosis have been identified, including disseminated superficial actinic porokeratosis, porokeratosis of Mibelli, linear porokeratosis, porokeratosis palmaris et plantaris disseminata, punctate porokeratosis, and porokeratosis ptychotropica (PP).1 Although risk factors for other forms of porokeratosis, such as UV exposure, immunosuppression, and genetic predisposition, have been identified, PP remains less understood. Clinically, PP typically presents as hyperkeratotic, verrucous plaques found bilaterally in the gluteal cleft and buttocks.2,3 These pruritic erythematous plaques and verrucous lesions can frequently resemble other perianal skin conditions, such as psoriasis, squamous cell carcinoma, verruca vulgaris, and candidiasis.3,4 This can make diagnosis more challenging, as it requires careful differentiation from other conditions when determining the most appropriate treatment. We report the case of a patient with an uncharacteristic presentation of PP that mimicked a herpes simplex virus infection.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

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Language

English

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