Case Presentation

An 82 year-old Caucasian woman was admitted to the hospitalwith marked splenomegaly and pancytopenia. Her primarycare physician noted splenomegaly on physical exam duringa recent visit, and a CT scan of the abdomen was performedas an outpatient which revealed a massively enlarged spleen.The patient admitted to losing up to 40 pounds over the pastsix months due to decreased appetite and early satiety. Shealso reported dyspepsia and a feeling of fullness in her bellyfor several months. The patient denied nausea, vomiting,constipation, or diarrhea. Other symptoms included increasedfatigue, chronically swollen legs, and frequent night sweats twoto three nights per week with occasional fevers. The patientdenied shortness of breath, cough, or chest pain. She complainedof urinary urgency and frequency.