Document Type

Abstract

Publication Date

2-11-2026

Academic Year

2025-2026

Comments

Presented at the 2026 Scholarly Inquiry (SI) Research Project Symposium.

Abstract

Introduction/Purpose: Obstructive sleep apnea (OSA) is characterized by upper airway closure during sleep, resulting in surges of sympathetic activity, elevated blood pressure and arterial oxygen desaturation. Over time, this can lead to systemic hypertension, congestive cardiac failure, and acute coronary syndrome. The current gold standard treatment is CPAP (continuous positive pressure airway),  which reduces blood pressure and heart rate while improving oxygen saturation. However, the effect of CPAP treatment on dyslipidemia is less understood.  Accordingly, this study aims to determine the effect of adherent CPAP use on dyslipidemia in our sleep medicine practice in Philadelphia.

Methods: The retrospective medical chart review compared patients with OSA who adhere to a minimum nightly average CPAP use of four hours to patients with OSA who are nonadherent to this standard. Using dual chart review methodology for enhanced accuracy, total cholesterol, LDL, HDL, and triglyceride levels were extracted by certified students from EPIC charts along with demographics and covariates from Jefferson Sleep Center patients. SPSS and SAS 9.4 software will be used to analyze descriptive statistics for 32 patients regarding patient demographics and lipid levels (TC, LDL, TG, and HDL), followed by a two-sample T-test to compare mean lipid levels between our two groups. Multiple regression analysis will control for demographics and covariates such as medication use.

Results/Conclusions: Results and analysis are pending and will be included in my final poster that I hypothesize will demonstrate improved TC, LDL, TG, and HDL levels in OSA patients with adherent CPAP use.

Additional Files
Miller_Evelyn_poster.pdf (171 kB)

Language

English

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