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inSIGHT

Abstract

Neovascular age-related macular degeneration (nAMD) requires frequent monitoring to identify recurrent exudation and guide treatment with anti-vascular endothelial growth factor (VEGF) therapy.1 Clinic-based optical coherence tomography (OCT) plays a central role in management but provides only intermittent assessments of a disease that changes over time. Home-use OCT technologies have recently been developed as a possible solution, allowing patients to perform self-imaging with remote clinician review and artificial intelligence (AI)-assisted analysis. This rapid review summarizes current evidence on home-use OCT for nAMD, including feasibility, diagnostic performance, clinical usefulness, and challenges related to implementation. Findings from feasibility studies, AI validation analyses, observational cohorts, and real-world use suggest that home OCT can reliably detect retinal fluid, identify disease activity earlier than standard care, and help support more individualized treatment approaches.

However, important challenges remain, including patient selection, adherence, workflow integration, reimbursement, and equity. Overall, home-use OCT appears to be a promising addition to nAMD management, although further prospective and controlled studies are needed to better define its role.

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