Acute Neurological Toxicity (NT) and Long-Term Outcomes in High-grade Glioma RTOG Trials

Authors

Y. R. Lawrence, Thomas Jefferson University and Hospitals
M. Wang, Radiation Therapy Oncology Group
A. P. Dicker, Thomas Jefferson University and HospitalsFollow
D. W. Andrews, Thomas Jefferson University
W. J. Curran, Emory UniversityFollow
J. M. Michalski, Washington University School of MedicineFollow
L. Souhami, McGill University Health CentreFollow
W. A. Yung, University of Texas
M. Mehta, University of Wisconsin Medical SchoolFollow

Abstract

Background: Treatment of high-grade glioma consists of fractionated radiation therapy (RT) ± chemotherapy. The incidence/significance of neurological toxicity (NT) in this disease is not known. We evaluated the relationship between acute and chronic NT, and ultimate outcome, as well as risk factors for NT from the RTOG database.

American Society of Clinical Oncology (ASCO) 46th Annual Meeting June 4-8, Chicago, IL.

Recommended Citation

Lawrence, Y. R.; Wang, M.; Dicker, A. P.; Andrews, D. W.; Curran, W. J.; Michalski, J. M.; Souhami, L.; Yung, W. A.; and Mehta, M. (2010) "Acute Neurological Toxicity (NT) and Long-Term Outcomes in High-grade Glioma RTOG Trials," Bodine Journal: Vol. 3: Iss. 1, Article 6.
DOI: https://doi.org/10.29046/TBJ.003.1.005
Available at: https://jdc.jefferson.edu/bodinejournal/vol3/iss1/6