The Role of HIF1-Alpha in Regulating Carbonic Anhydrases within the Nucleus Pulposus
Carbonic anhydrases plays an essential role in maintaining the homeostasis of the disc microenvironment due to its hypoxic nature.
HIF1-alpha plays a crucial role in CA regulation within NP cells and as a result disc degeneration may be related to inappropriate CA regulation.
Presentation: 12 minutes
Recommended CitationBatista, MD, Philip and Risbud, PhD, Makarand V., "The Role of HIF1-Alpha in Regulating Carbonic Anhydrases within the Nucleus Pulposus" (2014). Department of Surgery Resident Research Day. Paper 3.