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Introduction: Human papilloma virus (HPV) vaccination remains a controversial topic with low rates of vaccination completion. According to a 2017 National Immunization Survey, only 49% of adolescents were up to date (UTD) on their HPV vaccination, an alarming statistic given its importance in reducing HPV-related cancers. This project seeks to determine the effectiveness of pediatric order sets in affecting rates of HPV vaccine administration in a large urban family medicine practice.

Methods: A retrospective, qualitative chart review was conducted on patients nine years or older seen at Jefferson Family Medicine Associates in Philadelphia, PA from April 2019 to April 2020. Of the 1177 encounters, status was determined as followed: HPV series completed, vaccine series in progress and currently UTD, or HPV vaccine due at encounter but not administered (“missed opportunity”).

Results: Of the 49 encounters of patients older than 15 years and not UTD before the encounter, 29% were a “missed opportunity.” None of these encounters utilized the pediatric order sets. Of the 251 encounters of patients between the age of 11-14 years, 21% were a “missed opportunity.” Of these, 87% of the encounters did not utilize smart sets.

Discussion: These results demonstrate that a majority of missed opportunities for HPV immunization are during encounters where the pediatric order sets were not being utilized. Although further studies are needed to address missed opportunities, this data illustrates that pediatric order sets have the potential to improve rates of HPV vaccination administration and completion at a family medicine practice.