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Surgical Site Infection (SSI) after total joint arthroplasty (TJA) is a rare but devastating complication1. In spite of improvement in the prevention of SSI, these infections are still a signi­ficant cause of morbidity in surgical patients2. Management of Hospital Acquired infections (HAI) including SSI poses a huge economic burden on healthcare3. As part of the mission to reduce the burden of HAI, the Centers for Disease Control and Prevention (CDC) has issued guidelines for the prevention of SSI that are currently being updated4. In addition, CDC requires all hospitals to report HAI through the National Healthcare Safety Network (NHSN) surveillance program.

It is believed that identi­fication of patient-related risk factors and their reversal in some cases can lead to a reduction in SSI5. Although several studies have been performed to determine the risk factors of SSI following TJA1,6, risk factors for SSI as defi­ned by the CDC and required to be reported has not been fully evaluated. The objective of this case-control study was to determine the patient-related risk factors for SSI following primary and revision TJA using our institutional database on TJA and the data generated by the NHSN surveillance.

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