Thomas Jefferson University Research Magazine



What is the molecular basis for pancreatic cancer's aggressive nature and resistance to treatment? Elda Grabocka, PhD, assistant professor of cancer biology and surgery, is working to find out. Last year, she received both a Margaret Q. Landenberger Research Foundation grant—which supports promising early-stage medical researchers—and her first NIH/NCI R01 grant. She has also received a V Foundation Scholar Research Award and a W.W. Smith Charitable Foundation grant. Her research investigates pancreatic cancer’s ability to hijack the mechanisms by which normal cells adapt stressors. Ratcheting up that mechanism allows tumors to grow under adverse conditions and it enhances their resistance to chemotherapy.