Document Type
Article
Publication Date
5-21-2025
Abstract
Idiopathic Intracranial hypertension (IIH), also referred to as pseudotumor cerebri, is a term used to describe increased intracranial pressure in the absence of a known identifiable secondary cause. Despite advancements of neuroimaging techniques, imaging of the pathological underpinnings in the diagnosis of IIH has been limited. Although the causation of IIH has been ascribed to increased Cerebrospinal Fluid production and disordered drainage through the dural sinuses, new evidence shows that the glymphatic system which is an alternate pathway of drainage is likely to play a pivotal role. In this review, we address the pathophysiological underpinnings in the causation of IIH and discusses characteristic anatomical imaging findings on conventional MRI and explore the role of advanced imaging techniques.
Recommended Citation
Basimah, Albalooshy; Faro, Scott; Yuan, Hsiangkuo; Talekar, Kiran; Mondel, Prabath; Qiu, Enchao; and Chaganti, Joga, "Imaging Hallmarks of Idiopathic Intracranial Hypertension and Insights Into Pathogenesis" (2025). Department of Radiology Faculty Papers. Paper 172.
https://jdc.jefferson.edu/radiologyfp/172
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
PubMed ID
40470302
Language
English
Included in
Diagnosis Commons, Hemic and Immune Systems Commons, Musculoskeletal, Neural, and Ocular Physiology Commons, Nervous System Diseases Commons, Radiology Commons
Comments
This article, first published by Frontiers Media, is the author's final published version in Frontiers in Radiology, Volume 5, 2025, Article number 1605777.
The published version is available at https://doi.org/10.3389/fradi.2025.1605777.
Copyright © 2025 Basimah, Faro, Yuan, Talekar, Mondel, Qiu and Chaganti