Rethinking Sepsis

Clifford S. Deutschman, MS, MD, FCCM, University of Pennsylvania

Dr. Clifford Deutschman is a Professor of Anesthesiology and Critical Care and Director of Sepsis research program at the Perelman School of Medicine at the University of Pennsylvania. His current research interest includes using molecular and cellular biologic techniques to study the effects of sepsis on organ function. Current projects involve changes in the liver, lung and heart. In addition, he is examining the function of specific circulating cells such as platelets and neutrophils. These investigations involve collaborations with a number of other investigators at the University of Pennsylvania, other US institutions and throughout the world.



1. Be familiar with current definitions of sepsis, septic shock, severe sepsis and organ dysfunction.

2. Up-to-date data on the epidemiology of sepsis.

3. Be aware of the current state of therapy.

4. Discuss several "heretical" theories that might explain our inability to fully treat this deadly disorder.