Small cell carcinoma of the breast (SCCB) is a rare, highly aggressive neoplasm first reported in 1983. With striking histologic similarity to small cell carcinoma of the lung, it is comprised of small cells with relatively large, hyperchromatic nuclei and scanty cytoplasm. While capable of hormone secretion, this is a rare occurrence in this variant of small cell carcinoma. Patients typically present with a suspicious breast mass confirmed on imaging, with variable lymph node invasion.
Recommended CitationCarlson, Victor; Cotzia, MD, Paolo; and Palazzo, MD, Juan P., "Small Cell Carcinoma of the Breast" (2014). Department of Pathology Honors Program Student Research Symposium. Poster 32.