Title

Small Cell Carcinoma of the Breast

Authors

Victor Carlson, Thomas Jefferson UniversityFollow
Paolo Cotzia, MD, Department of Pathology, Anatomy, & Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PAFollow
Juan P. Palazzo, MD, Department of Pathology, Anatomy, & Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PAFollow

Document Type

Poster

Publication Date

6-2014

Abstract

INTRODUCTION

Small cell carcinoma of the breast (SCCB) is a rare, highly aggressive neoplasm first reported in 1983. With striking histologic similarity to small cell carcinoma of the lung, it is comprised of small cells with relatively large, hyperchromatic nuclei and scanty cytoplasm. While capable of hormone secretion, this is a rare occurrence in this variant of small cell carcinoma. Patients typically present with a suspicious breast mass confirmed on imaging, with variable lymph node invasion.

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