T-CELL RECEPTOR, NORMALLY
T-cell receptors reside on the surface of T-cells, and recognize a specific antigen presented by an MHC molecule
Next, the T-cells become either CD4 or CD8 cells
Co-stimulation is a key step in activating the T-cell; B7 proteins on the surface of antigen-presenting cells interact with CD28/CTLA-4 receptors on the T-cell.
Recommended CitationEvron, Emily and Rubin, MD, Emanual, "Personalized Immune Therapy For Cancer A Potential Game-Changing Treatment" (2014). Department of Pathology Honors Program Student Research Symposium. Poster 28.