Case Report: A 61-year-old-woman with a past medical history significant for hypertension, bipolar disorder, obstructive sleep apnea and chronic obstructive pulmonary disease presented with diffusive lymphadenopathy suspicious for lymphoma. A lymph node in her right groin was biopsied by fine needle aspiration and showed atypical cells, but was not diagnostic. An excisional biopsy of the 2 x 2 cm lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected. A CT scan revealed the presence of a large nasopharyngeal mass that following surgical removal was diagnosed as MCC. Treatment with etoposide and cisplatin and radiation were instituted. The patient went on to develop radiation-induced pneumonitis and cystitis, fungal sepsis, and deep vein thromboses. The patient was later transferred to a long-term acute care facility.
Recommended CitationWu, MD, Karen N.; McCue, MD, Peter A.; Wang, PhD, Zi-Xuan; and Witkiewicz, MD, Agnieszka K., "Detection of Merkel Cell Carcinoma Polyomavirus in Mucosal Merkel Cell Carcinoma" (2009). Department of Pathology, Anatomy, and Cell Biology Faculty Papers. Paper 27.