Document Type


Publication Date

January 2008


This article has been peer reviewed. It is the authors' final version prior to publication in Surgical Oncology Clinics of North America 17(1):157-73, January 2008. The published version is available at DOI: 10.1016/j.soc.2007.10.002, copyright © 2008 by Elsevier, Inc.


Differentiated thyroid cancer is characterized by an excellent long-term prognosis, which unlike other head and neck carcinomas, is not influenced definitively by regional lymph node metastasis. The relative rarity of the disease, together with its tendency for delayed metastasis and its low mortality, makes a prospective randomized trial comparing treatment outcomes difficult. As a result, the effect of cervical lymph node metastases on survival is unclear, making meaningful recommendations for their management somewhat subjective. This article discusses guidelines for the management of the neck in differentiated.



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