Document Type


Publication Date

May 2007


This article has been peer reviewed. It is the author's final version prior to publication in Facial Plastic Surgery Clinics of North America 15(2):247-250, 2007. The published version is available at Copyright © 2007 Elsevier, Inc.


Products approved by the US Food and Drug Administration (FDA) for one use are often put to other uses. This practice, known colloquially as "off-label usage," is neither illegal nor unethical. Physicians can and should pursue scientifically sound use supported by medical evidence. The FDA requires only that we:

--Be well informed about the product
--Base its use on firm scientific rationale and sound medical evidence, if available
--Maintain records of the product’s use and effects
--Carry out good medical practice
--Use good judgment
--Consider the best interests of the patient before all else



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