Document Type
Article
Publication Date
4-2025
Abstract
Chronic subdural hematoma (cSDH) presents a multifaceted challenge in contemporary neurological practice, necessitating innovative therapeutic strategies. This comprehensive review explores the convergence of two promising interventions: statins and middle meningeal artery (MMA) Embolization. With cSDH incidence on the rise, particularly among the aging population and those with long-term anticoagulant usage, the traditional surgical avenues face limitations in recurrence rates and associated risk factors. Statins, heralded for their anti-inflammatory, vasculogenic, and angiogenic properties, are emerging as potential allies in cSDH management. Concurrently, MMA embolization offers a nuanced approach to target the neomembrane's blood supply, with evidence supporting its efficacy and safety. However, the synthesis of MMA embolization with statins remains relatively unexplored, presenting a complex interplay between inflammation modulation and blood supply interruption.
Recommended Citation
Musmar, Basel; Roy, Joanna M.; Spellicy, Samantha; Tjoumakaris, Stavropoula I.; Gooch, Michael R.; Rosenwasswer, Robert H.; Hasan, David; and Jabbour, Pascal, "Statins and Middle Meningeal Artery Embolization: A Literature Review in the Treatment of Chronic Subdural Hematoma" (2025). Department of Neurosurgery Faculty Papers. Paper 263.
https://jdc.jefferson.edu/neurosurgeryfp/263
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
PubMed ID
40340286
Language
English
Comments
This article is the author’s final published version in the Journal of Neurosurgical Sciences, Volume 69, Issue 2, April 2025, Pages 218-224.
The published version is available at https://doi.org/10.23736/s0390-5616.25.06426-4. Copyright © 2025 THE AUTHORS.