Trsper: a web-based application for Archimedes spiral analysis
Document Type Article
This article is the author’s final published version in mHealth, Volume 8, January 2022 Article number 3.
The published version is available at https://doi.org/10.21037/mhealth-21-16. Copyright © mHealth.
Background: We built a web-based application of the Archimedes spiral exam that implements clinically validated spiral metrics and tested drawing instructions to define a clinical workflow.
Results: Principal components analysis of calculated metrics revealed that the experiments grouped by instruction set and by subject. Mean Euclidean distance between experiments represented as 11-dimensional vectors revealed that consistency varied among instruction tasks and that drawing with a stylus produced more consistent results than did using the dominant index finger. Using experimental data and simulated abnormal spirals, we designed a decision support system that accurately identifies potentially abnormal spirals.
Conclusions: We built and validated a robust digital implementation of the Archimedes spiral exam and recommend a sensitive and specific workflow on the basis of data gathered from healthy volunteers.