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Opioid overdoses in the United States continue to persist as a significant public health problem and cause of morbidity and mortality. Pennsylvania and Philadelphia have some of the highest rates of overdose death nationwide. Patients who experience and survive an overdose event are at high risk for experiencing another. The objective of this study was to identify secondary prevention strategies used throughout the United States to engage opioid users and direct them to definitive treatment for addiction. Programs throughout the United States provided by hospitals, non-profits, and government agencies were queried using search terms “post overdose care” and “overdose follow up”. Results where then characterized by patient engagement strategy. Three predominant patient strategies were identified: “warm hand off”, “field provider facilitated”, and “follow up.” Similar resources in Philadelphia were then searched for and results were compared with the strategies identified at the national level. Philadelphia was found to have one program using the “field provider facilitated” engagement strategy, but no programs utilizing “warm hand off” or “follow up.” Philadelphia’s public health institutions looking to engage a larger audience of high-risk opioid users should consider implementation of secondary prevention strategies such as “warm hand off” and “follow up.”