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AE Leader, College of Population Health, Thomas Jefferson University, Philadelphia, PA.


Philadelphia has high rates of adolescent human papillomavirus (HPV) vaccine series completion. The purpose of this study was to examine factors associated with HPV vaccine series completion in adolescent Philadelphians. A secondary data analysis was conducted using vaccination data from the Philadelphia Immunization Information System. A total of 50,185 participants born between 2000 and 2003, inclusive, received at least 1 dose of HPV vaccine before 8/31/2015. Series completion was defined by receipt of at least 3 doses of HPV vaccine. Only 49.9% of females and 45.1% of males completed the HPV vaccine series. Multivariable logistic regression analysis showed that for females, Hispanic (OR 1.41, 95% CI 1.28, 1.56) and Asian (OR 1.76, 95% CI 1.53, 2.03) race/ethnicity were associated with series completion when accounting for differences in income and age. Lower-income females were less likely to complete the series than high-income females (≤100% Federal Poverty Guidelines, Family of [FPG]: OR 0.86, 95% CI 0.77, 0.95; 101-150% FPG: OR 0.82, 95% CI 0.75, 0.90; 151-200% FPG: OR 0.90, 95% CI 0.82-0.98). Hispanic (OR 1.42, 95% CI 1.28, 1.58) and Asian (OR 1.72, 95% CI 1.48, 2.00) males were more likely than white males to complete the series. For males, only the 101-150% FPG income category was associated with a different completion rate (OR 0.87, 95% CI 0.79, 0.96) than the >200% FPG income category. These results indicate that Hispanic and Asian race/ethnicity are predictors of HPV vaccine series completion in Philadelphia adolescents. Lower-income Philadelphia females, and some low-income males, are less likely to complete the series than higher-income adolescents. Efforts to improve series completion should aim at improving rates in African American and white adolescents and in low-income girls.

Presentation: 36:18