Aging predisposes to increased morbidity and lethality to infectious diseases, which becomes apparent with the high mortality rates suffered by older people when infected with influenza virus or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At the root of this increased susceptibility to infections, is the wide-spread deterioration of the immune system.
Stotesbury, Colby and Sigal, Luis J., "Dysregulated anti-viral innate immune cascade during aging." (2021). Department of Microbiology and Immunology Faculty Papers. Paper 123.
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This article has been peer reviewed. It was published in: Aging.
Volume 13, Issue 2, 2021, Pages 1566-1567.
The published version is available at DOI: 10.18632/aging.202588
Copyright © 2021 Stotesbury and Sigal
This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.