Manuscripts from 2023
Identification of Collaborative Cross Mouse Strains Permissive to Salmonella Enterica Serovar Typhi Infection, Kishore Alugupalli, Sudeep Kothari, Matthew P Cravens, Justin A Walker, Darren T Dougharty, Gregory S. Dickinson, Louis A Gatto, Andreas J Bäumler, Tamding Wangdi, Darla R Miller, Fernando Pardo-Manuel de Villena, and Linda D Siracusa
Chlamydia Trachomatis Subverts Alpha-Actinins To Stabilize Its Inclusion, A. Haines, J. Wesolowski, and F. Paumet
A Rodent Model for Dirofilaria Immitis, Canine Heartworm: Parasite Growth, Development, and Drug Sensitivity in NSG Mice, Jessica A. Hess, Mark L. Eberhard, Marcelo Segura-Lepe, Kathrin Grundner-Culemann, Barbara Kracher, Jeffrey Shryock, John Harrington, and David Abraham
Design and Preclinical Evaluation of a Universal SARS-CoV-2 mRNA Vaccine, Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J. Sigal, Renhuan Xu, and Huabin Zhu
Effects of Adjuvants in a Rabies-Vectored Ebola Virus Vaccine on Protection From Surrogate Challenge, Catherine Yankowski, Drishya Kurup, Christoph Wirblich, and Matthias J. Schnell
Manuscripts from 2022
The Lack of Natural IgM Increases Susceptibility and Impairs Anti-Vi Polysaccharide IgG Responses in a Mouse Model of Typhoid, Akhil S. Alugupalli, Matthew P. Cravens, Justin A. Walker, Dania Gulandijany, Gregory S. Dickinson, Genevieve Lewis, Gudrun F. Debes, Dieter M. Schifferli, Andreas J. Bäumler, and Kishore R. Alugupalli
The Immune Synapses Reveal Aberrant Functions of CD8 T Cells During Chronic HIV Infection, Nadia Anikeeva, Maria Steblyanko, Leticia Kuri-Cervantes, Marcus Buggert, Michael R. Betts, and Yuri Sykulev
Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines., Valentina Ceglia, Sandra Zurawski, Monica Montes, Mitchell Kroll, Aurélie Bouteau, Zhiqing Wang, Jerome Ellis, Botond Z Igyártó, Yves Lévy, and Gerard Zurawski
Attenuation of Relapsing Fever Neuroborreliosis in Mice by IL-17A Blockade, Meihui Cheng, Jingwen Xu, Kaiyun Ding, Jing Zhang, Wei Lu, Jiansheng Liu, Jiahong Gao, Kishore R Alugupalli, and Hongqi Liu
Is Strongyloides Stercoralis Hyperinfection Induced by Gglucocorticoids a Result of Both Suppressed Host Immunity and Altered Parasite Genetics?, De'Broski R Herbert, Jonathan D C Stoltzfus, Heather L Rossi, and David Abraham
Intracellular Monitoring by Dendritic Cells - A New Way to Stay Informed - from a Simple Scavenger to an Active Gatherer, Christopher Herbst, Larry A Harshyne, and Botond Z Igyártó
"Don't Look Up" Your Science-Herd Immunity or Herd Mentality?, Botond Z Igyártó
A Single Dose of the Deactivated Rabies-Virus Vectored COVID-19 Vaccine, CORAVAX, Is Highly Efficacious and Alleviates Lung Inflammation in the Hamster Model, Drishya Kurup, Christoph Wirblich, Leila Zabihi Diba, Rachael Lambert, Megan Watson, Noor Shaikh, Holly Ramage, Charalambos Solomides, and Matthias J Schnell
Preprint Highlight: Vimentin Intermediate Filaments Organize Organellar ER Architecture in Response to Stress, Adriana Mantegazza
Interferon Partly Dictates a Divergent Transcriptional Response in Poxvirus-Infected and Bystander Inflammatory Monocytes, Carolina R Melo-Silva, Marisa I Roman, Cory J Knudson, Lingjuan Tang, Ren-Huan Xu, Michel Tassetto, Patrick Dolan, Raul Andino, and Luis J. Sigal
Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses, Sonia Ndeupen, Aurélie Bouteau, Christopher Herbst, Zhen Qin, Sonya Jacobsen, Nicholas E Powers, Zachary Hutchins, Drishya Kurup, Leila Zabihi Diba, Megan Watson, Holly Ramage, and Botond Z. Igyártó
Pre-exposure to mRNA-LNP Inhibits Adaptive Immune Responses and Alters Innate Immune Fitness in an Inheritable Fashion, Zhen Qin, Aurélie Bouteau, Christopher Herbst, and Botond Z. Igyártó
Arsenic Toxicity on Metabolism and Autophagy in Adipose and Muscle Tissues, Seung-Hyun Ro, Jiyoung Bae, Yura Jang, Jacob Myers, Soonkyu Chung, Jiujiu Yu, Sathish Kumar Natarajan, Rodrigo Franco, and Hyun-Seob Song
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells., Yung-Hsuan Wu, Shu-Ting Mo, I-Ting Chen, Fu-Yi Hsieh, Shie-Liang Hsieh, Jianke Zhang, and Ming-Zong Lai
Manuscripts from 2021
Development of a recombinant vaccine against human onchocerciasis., David Abraham, John Graham-Brown, Darrick Carter, Sean A. Gray, Jessica A. Hess, Benjamin L. Makepeace, and Sara Lustigman
Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs, Nadia Anikeeva, Sergey Panteleev, Nicholas W Mazzanti, Mizue Terai, Takami Sato, and Yuri Sykulev
Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing., Maria Ferez, Cory J. Knudson, Avital Lev, Eric B. Wong, Pedro Alves-Peixoto, Lingjuan Tang, Colby Stotesbury, and Luis J. Sigal
Cross Talk between ARF1 and RhoA Coordinates the Formation of Cytoskeletal Scaffolds during Chlamydia Infection, Adam Haines, Jordan Wesolowski, Nathan M Ryan, Tiago Monteiro-Brás, and Fabienne Paumet
Targeting human langerin promotes HIV-1 specific humoral immune responses., Jérôme Kervevan, Aurélie Bouteau, Juliane S Lanza, Adele Hammoudi, Sandra Zurawski, Mathieu Surenaud, Lydie Dieudonné, Marion Bonnet, Cécile Lefebvre, Hakim Hocini, Romain Marlin, Aurélie Guguin, Barbara Hersant, Oana Hermeziu, Elisabeth Menu, Christine Lacabaratz, Jean-Daniel Lelièvre, Gerard Zurawski, Véronique Godot, Sandrine Henri, Botond Z. Igyártó, Yves Levy, and Sylvain Cardinaud
Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection., Cory J Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J C Lin, Ying K Tam, Drew Weissman, Norbert Pardi, and Luis J. Sigal
Inactivated rabies virus vectored SARS-CoV-2 vaccine prevents disease in a Syrian hamster model., Drishya Kurup, Delphine C Malherbe, Christoph Wirblich, Rachael Lambert, Adam J Ronk, Leila Zabihi Diba, Alexander Bukreyev, and Matthias J. Schnell
Comparison of Lethal and Nonlethal Mouse Models of Orientia tsutsugamushi Infection Reveals T-Cell Population-Associated Cytokine Signatures Correlated with Lethality and Protection, Alison Luce-Fedrow, Suchismita Chattopadhyay, Teik-Chye Chan, Gregory Pearson, John B. Patton, and Allen L. Richards
A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19., Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, and Alexander Bukreyev
Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells., Carolina R Melo-Silva, Pedro Alves-Peixoto, Natasha Heath, Lingjuan Tang, Brian Montoya, Cory J Knudson, Colby Stotesbury, Maria Ferez, Eric B. Wong, and Luis J. Sigal
The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory, Sonia Ndeupen, Zhen Qin, Sonya Jacobsen, Aurélie Bouteau, Henri Estanbouli, and Botond Z. Igyártó
A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue, Rama Devudu Puligedda, Fetweh H Al-Saleem, Christoph Wirblich, Chandana Devi Kattala, Marko Jović, Laura Geiszler, Himani Devabhaktuni, Giora Z Feuerstein, Matthias J. Schnell, Markus Sack, Lawrence L Livornese, and Scott K Dessain
Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice, Nathan M Ryan, Jessica A. Hess Ligas, Fernando Pardo-Manuel de Villena, Benjamin E Leiby, Ayako Shimada, Lei Yu, Amir Yarmahmoodi, Nikolai Petrovsky, Bin Zhan, Maria Elena Bottazzi, Benjamin L Makepeace, Sara Lustigman, and David Abraham
Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8+ T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation, Corinne J. Smith and Christopher M. Snyder
Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth., Lauren E. Springer, John B. Patton, Tingting Zhan, Arnold B. Rabson, Hsin-Ching Lin, Tim Manser, James B. Lok, Jessica A. Hess, and David Abraham
Dysregulated anti-viral innate immune cascade during aging., Colby Stotesbury and Luis J. Sigal
SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms, Christine Vazquez, Sydnie E Swanson, Seble G Negatu, Mark Dittmar, Jesse Miller, Holly Ramage, Sara Cherry, and Kellie A Jurado
Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion., Shunchuan Zhang, Lauren E Springer, Han-Zhi Rao, Renee G Espinosa Trethewy, Lindsey M Bishop, Meaghan H Hancock, Finn Grey, and Christopher M. Snyder
Manuscripts from 2020
Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19., Paolo Antonio Ascierto, Bernard Fox, Walter Urba, Ana Carrizosa Anderson, Michael B Atkins, Ernest C Borden, Julie Brahmer, Lisa H Butterfield, Alessandra Cesano, Daniel Chen, Tanja de Gruijl, Robert O Dillman, Charles G Drake, Leisha A Emens, Thomas F Gajewski, James L Gulley, F Stephen Hodi, Patrick Hwu, David Kaufman, Howard Kaufman, Michael Lotze, Douglas G McNeel, Kim Margolin, Francesco Marincola, Michael J Mastrangelo, Marcela V Maus, David R Parkinson, Pedro J Romero, Paul M Sondel, Stefani Spranger, Mario Sznol, George J Weiner, Jon M Wiggington, and Jeffrey S Weber
STXBP2-R190C Variant in a Patient With Neonatal Hemophagocytic Lymphohistiocytosis (HLH) and G6PD Deficiency Reveals a Critical Role of STXBP2 Domain 2 on Granule Exocytosis, Nathalia Benavides, Waldo A Spessott, Maria L Sanmillan, Marcelo Vargas, Mylynda S Livingston, Nissa Erickson, Tamara C Pozos, Margaret E McCormick, Emilia Scharrig, Yoav H Messinger, and Claudio G. Giraudo
Human t-cell leukemia virus type 1 and strongyloides stercoralis: Partners in pathogenesis, Adam Dykie, Tharaka Wijesinghe, Arnold B Rabson, Kiran Madugula, Christian Farinas, Sydney Wilson, David Abraham, and Pooja Jain
Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species, Julia Hunka, John T. Riley, and Gudrun F. Debes
Rabies virus-based COVID-19 vaccine CORAVAX™ induces high levels of neutralizing antibodies against SARS-CoV-2., Drishya Kurup, Christoph Wirblich, Holly Ramage, and Matthias J Schnell
Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides., Azad Mamedov, Nadezhda Vorobyeva, Ioanna Filimonova, Maria Zakharova, Ivan Kiselev, Vitalina Bashinskaya, Natalia Baulina, Alexey Boyko, Alexander Favorov, Olga Kulakova, Rustam Ziganshin, Ivan Smirnov, Alina Poroshina, Igor Shilovskiy, Musa Khaitov, Yuri Sykulev, Olga Favorova, Valentin Vlassov, Alexander Gabibov, and Alexey Belogurov
Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation., Colby Stotesbury, Eric B Wong, Lingjuan Tang, Brian Montoya, Cory J Knudson, Carolina R Melo-Silva, and Luis J Sigal
Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells., Qingtai Su, Aurélie Bouteau, Jacob Cardenas, Balaji Uthra, Yuanyaun Wang, Cynthia Smitherman, Jinghua Gu, and Botond Z. Igyártó
Manuscripts from 2019
TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3., John P. Dowling, Mohamed Alsabbagh, Christina Del Casale, Zheng-Gang Liu, and Jianke Zhang
Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans., Parakkal Jovvian George, Jessica A. Hess, Sonia Jain, John B. Patton, Tingting Zhan, Nancy Tricoche, Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, David Abraham, and Sara Lustigman
Rabies-based vaccine induces potent immune responses against Nipah virus., Rohan Keshwara, Thomas Shiels, Elena Postnikova, Drishya Kurup, Christoph Wirblich, Reed F. Johnson, and Matthias J. Schnell
Inactivated Rabies Virus-Based Ebola Vaccine Preserved by Vaporization Is Heat-Stable and Immunogenic Against Ebola and Protects Against Rabies Challenge., Drishya Kurup, Christine R. Fisher, Todd G. Smith, Tiago Abreu-Mota, Yong Yang, Felix R. Jackson, Nadia Gallardo-Romero, Richard Franka, Victor Bronshtein, and Matthias J. Schnell
Incorporating B cell activating factor (BAFF) into the membrane of rabies virus (RABV) particles improves the speed and magnitude of vaccine-induced antibody responses., Joseph R Plummer and James P McGettigan
From Vaccine Vector to Oncomodulation: Understanding the Complex Interplay between CMV and Cancer., Nicole A. Wilski and Christopher M. Snyder
Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy., Eric B. Wong, Brian Montoya, Maria Ferez, Colby Stotesbury, and Luis J. Sigal
Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node., Eric B. Wong, Brian Montoya, Colby Stotesbury, Maria Ferez, Ren-Huan Xu, and Luis J. Sigal
Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response., Yi Yang, Thea L. Willis, Robert W. Button, Conor J. Strang, Yuhua Fu, Xue Wen, Portia R.C. Grayson, Tracey Evans, Rebecca J. Sipthorpe, Sheridan L. Roberts, Bing Hu, Jianke Zhang, Boxun Lu, and Shouqing Luo
RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development., Xuhua Zhang, John P. Dowling, and Jianke Zhang
Manuscripts from 2018
Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever., Tiago Abreu-Mota, Katie R. Hagen, Kurt Cooper, Peter B. Jahrling, Gene Tan, Christoph Wirblich, Reed F. Johnson, and Matthias J. Schnell
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease., Marcus Buggert, Son Nguyen, Laura M. McLane, Maria Steblyanko, Nadia Anikeeva, Dominic Paquin-Proulx, Perla M Del Rio Estrada, Yuria Ablanedo-Terrazas, Kajsa Noyan, Morgan A. Reuter, Korey Demers, Johan K. Sandberg, Michael A. Eller, Hendrik Streeck, Marianne Jansson, Piotr Nowak, Anders Sönnerborg, David H. Canaday, Ali Naji, E. John Wherry, Merlin L. Robb, Steven G Deeks, Gustavo Reyes-Teran, Yuri Sykulev, Annika C. Karlsson, and Michael R. Betts
Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1, Sandra M. Cardona, Sangwon V. Kim, Kaira A. Church, Vanessa O. Torres, Ian A. Cleary, Andrew S. Mendiola, Stephen P. Saville, Stephanie S. Watowich, Jan Parker-Thornburg, Alejandro Soto-Ospina, Pedronel Araque, Richard M. Ransohoff, and Astrid E. Cardona
PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors., Dongshi Chen, Jingshan Tong, Liheng Yang, Liang Wei, Donna B. Stolz, Jian Yu, Jianke Zhang, and Lin Zhang
CD8+ T-cell responses in vaccination: Reconsidering targets and function in the context of chronic antigen stimulation, Gabriela L. Cosma and Laurence Eisenlohr
A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding., Bruno Hernáez, Juan Manuel Alonso-Lobo, Imma Montanuy, Cornelius Fischer, Sascha Sauer, Luis J. Sigal, Noemí Sevilla, and Antonio Alcamí
Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections., Isaac J. Jensen, Christina S. Winborn, Micaela G. Fosdick, Peng Shao, Mikaela M. Tremblay, Qiang Shan, Sandeep Kumar Tripathy, Christopher M. Snyder, Hai-Hui Xue, Thomas S. Griffith, Jon C. Houtman, and Vladimir P. Badovinac
Onchocerca volvulus: The Road from Basic Biology to a Vaccine., Sara Lustigman, Benjamin L. Makepeace, Thomas R. Klei, Simon A. Babayan, Peter Hotez, David Abraham, and Maria Elena Bottazzi
Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons., Margaret A. MacGibeny, Orkide O. Koyuncu, Christoph Wirblich, Matthias J. Schnell, and Lynn W. Enquist
Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum., John B. Patton, Sasisekhar Bennuru, Mark L. Eberhard, Jessica A. Hess Ligas, April R. Torigian, Sara Lustigman, Thomas B. Nutman, and David Abraham
Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease., Donna L. Perry, Louis M. Huzella, John G. Bernbaum, Michael R. Holbrook, Peter B. Jahrling, Katie R. Hagen, Matthias J. Schnell, and Reed F. Johnson
With some risk-taking and luck: A veterinarian's adventures in viral immunology., Luis J. Sigal
Manuscripts from 2017
Metabolite profiling of infection-associated metabolic markers of onchocerciasis., Sasisekhar Bennuru, Sara Lustigman, David Abraham, and Thomas B. Nutman
APRIL:TACI axis is dispensable for the immune response to rabies vaccination., Shannon L. Haley, Evgeni P. Tzvetkov, Andrew G. Lytle, Kishore R. Alugupalli, Joseph R. Plummer, and James P. McGettigan
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions., Alvaro Teijeira, Morgan C. Hunter, Erica Russo, Steven T Proulx, Thomas Frei, Gudrun F. Debes, Marc Coles, Ignacio Melero, Michael Detmar, Ana Rouzaut, and Cornelia Halin
Differentiation and Protective Capacity of Virus-Specific CD8, Vesselin T. Tomov, Olesya Palko, Chi Wai Lau, Ajinkya Pattekar, Yuhang Sun, Ralitza Tacheva, Bertram Bengsch, Sasikanth Manne, Gabriela L. Cosma, Laurence C. Eisenlohr, Timothy J. Nice, Herbert W. Virgin, and E. John Wherry
The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees?, Peter D. Walsh, Drishya Kurup, Dana L. Hasselschwert, Christoph Wirblich, Jason E. Goetzmann, and Matthias J. Schnell
Taking control: reorganization of the host cytoskeleton by Chlamydia., Jordan Wesolowski and Fabienne Paumet
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning., Jordan Wesolowski, Mary M. Weber, Agata Nawrotek, Cheryl A. Dooley, Mike Calderon, Claudette M. St Croix, Ted Hackstadt, Jacqueline Cherfils, and Fabienne Paumet
Manuscripts from 2016
Evaluating frequency and quality of pathogen-specific T cells., Nadia Anikeeva, Dolores Grosso, , and Yuri Sykulev
Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection., Sridhar Arumugam, Junfei Wei, Zhuyun Liu, David Abraham, Aaron Bell, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Sara Lustigman, and Thomas R Klei
YY1 Is Required for Germinal Center B Cell Development., Anupam Banerjee, Vishal Sindhava, Raja Vuyyuru, Vibha Jha, Suchita Hodewadekar, Tim Manser, and Michael L Atchison
Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation., John Bertin, Peter J. Gough, Jianke Zhang, John P. Dowling, and Yubo Cai
IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity., Phillip P. Domeier, Sathi Babu Chodisetti, Chetna Soni, Stephanie L. Schell, Melinda J. Elias, Eric B. Wong, Timothy K. Cooper, Daisuke Kitamura, and Ziaur S.M. Rahman
The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice., Jessica A. Hess Ligas, Bin Zhan, April R. Torigian, John B. Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J. Hotez, Thomas R. Klei, Sara Lustigman, and David Abraham
The Clock Is Ticking: Countdown to Metastases., Linda D. Siracusa and Karen M. Bussard
CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive Therapies., Corinne J Smith, Michael Quinn, and Christopher M Snyder
MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome., Xixi Zhang, Cunxian Fan, Haiwei Zhang, Qun Zhao, Yongbo Liu, Chengxian Xu, Qun Xie, Xiaoxia Wu, Xianjun Yu, Jianke Zhang, and Haibing Zhang
Manuscripts from 2015
The Onchocerciasis Vaccine for Africa-TOVA-Initiative., Peter J Hotez, Maria Elena Bottazzi, Bin Zhan, Benjamin L Makepeace, Thomas R Klei, David Abraham, David W Taylor, and Sara Lustigman
Rhabdovirus-based vaccine platforms against henipaviruses., Drishya Kurup, Christoph Wirblich, Heinz Feldmann, Andrea Marzi, and Matthias J. Schnell
Lymph node but not intradermal injection site macrophages are critical for germinal center formation and antibody responses to rabies vaccination., Andrew G Lytle, Shixue Shen, and James McGettigan
Endogenous antigen processing drives the primary CD4+ T cell response to influenza., Michael A Miller, Asha Purnima V Ganesan, Nancy Luckashenak, Mark Mendonca, and Laurence C. Eisenlohr
Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics., Christian K Pfaller, Roberto Cattaneo, and Matthias J. Schnell
Memory T Cells Specific for Murine Cytomegalovirus Re-Emerge after Multiple Challenges and Recapitulate Immunity in Various Adoptive Transfer Scenarios., Michael Quinn, Holly Turula, Mayank Tandon, Berthony Deslouches, Toktam Moghbeli, and Christopher M. Snyder
Murine CMV Infection Induces the Continuous Production of Mucosal Resident T Cells., Corinne J Smith, Sofia Caldeira-Dantas, Holly Turula, and Christopher M. Snyder
Manuscripts from 2014
Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents., Nadia Anikeeva, Yuri Sykulev, Edward J Delikatny, and Anatoliy V Popov
Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Junfei Wei, Danielle Ward, David Abraham, Sara Lustigman, Bin Zhan, and Thomas R. Klei
Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae., Sridhar Arumugam, Bin Zhan, David Abraham, Danielle Ward, Sara Lustigman, and Thomas R Klei
Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis., Sandra Bonne-Annee, Laura A. Kerepesi, Jessica A. Hess, Jordan Wesolowski, Fabienne Paumet, James B. Lok, Thomas J. Nolan, and David Abraham
MyD88-Dependent Immunity to a Natural Model of Vaccinia Virus Infection Does Not Involve Toll-Like Receptor 2., Michael L Davies, Janet J Sei, Nicholas A Siciliano, Ren-Huan Xu, Felicia Roscoe, Luis J Sigal, Laurence C. Eisenlohr, and Christopher C Norbury
Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI., Gregory S. Dickinson, PhD; Guizhi Sun; Richard J Bram; and Kishore Alugupalli
Interleukin-7-dependent B lymphocytes are required for the anti-pneumococcal polysaccharide response and protective immunity to Streptococcus pneumoniae, Gregory S. Dickinson, PhD; Raja Vuyyuru; Timothy L. Manser, PhD; John F. Kerney; and Kishore Alugupalli, PhD
Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses., Ziying Han, Jianhong Lu, Yuliang Liu, Benjamin Davis, Michael S Lee, Mark A Olson, Gordon Ruthel, Bruce D Freedman, Matthias J. Schnell, Jay E Wrobel, Allen B Reitz, and Ronald N Harty
Epithelial Immunization Induces Polyfunctional CD8+ T Cells and Optimal Mousepox Protection., Adam R Hersperger, Nicholas A Siciliano, Brian C DeHaven, Adam E. Snook, and Laurence C. Eisenlohr
Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model., Jessica A. Hess, Bin Zhan, Sandra Bonne-Annee, Jessica M. Deckman, Maria Elena Bottazzi, Peter J. Hotez, Thomas R R. Klei, Sara Lustigman, and David Abraham
