Manuscripts from 2025
AXL Signaling in Cancer: From Molecular Insights to Targeted Therapies, Monika Yadav, Akansha Sharma, Ketki Patne, Saba Tabasum, Jyoti Suryavanshi, Laxminarayan Rawat, Marc Machaalani, Marc Eid, Rana Singh, Toni Choueiri, Soumitro Pal, and Akash Sabarwal
Manuscripts from 2024
Monophosphoryl Lipid A-based Adjuvant to Promote the Immunogenicity of Multivalent Meningococcal Polysaccharide Conjugate Vaccines, Kishore Alugupalli
Characterization of Turbo, a TLR Ligand-Based Adjuvant for Glycoconjugate Vaccines, Kishore R. Alugupalli
Toward the Development of a Pan-Lyssavirus Vaccine, Sabrine Ben Hamed, Jacob Myers, Anisha Chandwani, Christoph Wirblich, Drishya Kurup, Nir Paran, and Matthias Schnell
The mRNA-LNP Vaccines - The Good, The Bad and The Ugly?, Botond Z. Igyártó and Zhen Qin
The Roles of CD4+ T Cell Help, Sex, and Dose in the Induction of Protective CD8+ T Cells Against a Lethal Poxvirus by mRNA-LNP Vaccines, Samita Kafle, Brian Montoya, Lingjuan Tang, Ying Tam, Hiromi Muramatsu, Norbert Pardi, and Luis Sigal
Specialized Contact Sites Regulate the Fusion of Chlamydial Inclusion Membranes, Christine Linton, Jordan Wesolowski, Anna Lobley, Toshiyuki Yamaji, Kentaro Hanada, and Fabienne Paumet
Immune Responses Drive Chorioretinitis and Retinal Pathology After Neonatal CMV Infection, Jessica L. McCord, John Y.S. Han, Ross E. Staudt, Nancy J. Philp PhD, and Christopher M. Snyder
Secreted IgM Modulates IL-10 Expression in B Cells, Shannon McGettigan, Lazaro Aira, Gaurav Kumar, Romain Ballet, Eugene Butcher, Nicole Baumgarth, and Gudrun Debes
Innate and Adaptive Immune Responses That Control Lymph-Borne Viruses in the Draining Lymph Node, Carolina R. Melo-Silva and Luis J. Sigal
The Development of a Rabies Virus-Vectored Vaccine Against Borrelia burgdorferi, Targeting BBI39, Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, and Matthias J. Schnell
Motif-VI Loop Acts as a Nucleotide Valve in the West Nile Virus NS3 Helicase, Priti Roy, Zachary Walter, Lauren Berish, Holly Ramage, and Martin McCullagh
Inactivated Rabies-Based Lassa Fever Virus Vaccine Candidate LASSARAB Protects Nonhuman Primates From Lethal Disease, Gabrielle Scher, Catherine Yankowski, Drishya Kurup, Nicole Josleyn, Eric Wilkinson, Jay Wells, Jesse Steffens, Ginger Lynn, Sean Vantongeren, Xiankun Zeng, Nancy Twenhafel, Kathleen Cashman, and Matthias Schnell
Manuscripts from 2023
Identification of Collaborative Cross Mouse Strains Permissive to Salmonella Enterica Serovar Typhi Infection, Kishore Alugupalli, Sudeep Kothari, Matthew P Cravens, Justin A Walker, Darren T Dougharty, Gregory S. Dickinson, Louis A Gatto, Andreas J Bäumler, Tamding Wangdi, Darla R Miller, Fernando Pardo-Manuel de Villena, and Linda D Siracusa
Extended-Synaptotagmin-1 and -2 Control T Cell Signaling and Function, Nathalia Benavides and Claudio G. Giraudo
IGG3 Subclass Antibodies Recognize Antigenically Drifted Influenza Viruses and SARS-CoV-2 Variants Through Efficient Bivalent Binding, Marcus J. Bolton, Jefferson J.S. Santos, Claudia P. Arevalo, Trevor Griesman, Megan Watson, Shuk Hang Li, Paul Bates, Holly Ramage, Patrick C. Wilson, and Scott E. Hensley
Chlamydia Trachomatis Subverts Alpha-Actinins To Stabilize Its Inclusion, A. Haines, J. Wesolowski, and F. Paumet
A Rodent Model for Dirofilaria Immitis, Canine Heartworm: Parasite Growth, Development, and Drug Sensitivity in NSG Mice, Jessica A. Hess, Mark L. Eberhard, Marcelo Segura-Lepe, Kathrin Grundner-Culemann, Barbara Kracher, Jeffrey Shryock, John Harrington, and David Abraham
Multiple and Consecutive Genome Editing Using i-GONAD and Breeding Enrichment Facilitates the Production of Genetically Modified Mice, Carolina R Melo-Silva, Cory J Knudson, Lingjuan Tang, Samita Kafle, Lauren E. Springer, Jihae Choi, Christopher M. Snyder, Yajing Wang, Sangwon V. Kim, and Luis J. Sigal
Design and Preclinical Evaluation of a Universal SARS-CoV-2 mRNA Vaccine, Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J. Sigal, Renhuan Xu, and Huabin Zhu
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates, Nathan M. Ryan, Jessica A. Hess, Erica J. Robertson, Nancy Tricoche, Cheri Turner, Jenn Davis, Nikolai Petrovsky, Melissa Ferguson, William J. Rinaldi, Valerie M. Wong, Ayako Shimada, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepece, Sean A. Gray, Darrick Carter, Sara Lustigman, and David Abraham
GP38 as a Vaccine Target for Crimean-Congo Hemorrhagic Fever Virus, Gabrielle Scher, Dennis A. Bente, Megan C. Mears, Maria N.B. Cajimat, and Matthias J. Schnell
Dietary L-Tryptophan Consumption Determines the Number of Colonic Regulatory T cells and Susceptibility to Colitis via GPR15, Nguyen Van, Karen Zhang, Rachel Wigmore, Anne Kennedy, Carolina DaSilva, Jialing Huang, Manju Ambelil, Jose Villagomez, Gerald O'Connor, Randy Longman, Miao Cao, Adam Snook, Michael Platten, Gerard Kasenty, Luis Sigal, George C Prendergast, and Sangwon Kim
Serotonin Reduction in Post-acute Sequelae of Viral Infection, Andrea Wong, Ashwarya Devason, Iboro Umana, Timothy Cox, Lenka Dohnalová, Lev Litichevskiy, Jonathan Perla, Patrick Lundgren, Zienab Etwebi, Luke Izzo, Jihee Kim, Monika Tetlak, Hélène Descamps, Simone Park, Stephen Wisser, Aaron McKnight, Ryan Pardy, Junwon Kim, Niklas Blank, Shaan Patel, Katharina Thum, Sydney Mason, Jean-Christophe Beltra, Michaël Michieletto, Shin Foong Ngiow, Brittany Miller, Megan Liou, Bhoomi Madhu, Oxana Dmitrieva-Posocco, Alex Huber, Peter Hewins, Christopher Petucci, Candice Chu, Gwen Baraniecki-Zwil, Leila Giron, Amy Baxter, Allison Greenplate, Charlotte Kearns, Kathleen Montone, Leslie Litzky, Michael Feldman, Jorge Henao-Mejia, Boris Striepen, Holly Ramage, Kellie Jurado, Kathryn Wellen, Una O'Doherty, Mohamed Abdel-Mohsen, Alan L Landay, Ali Keshavarzian, Timothy Henrich, Steven Deeks, Michael Peluso, Nuala Meyer, E. John Wherry, Benjamin Abramoff, Sara Cherry, Christoph Thaiss, and Maayan Levy
Effects of Adjuvants in a Rabies-Vectored Ebola Virus Vaccine on Protection From Surrogate Challenge, Catherine Yankowski, Drishya Kurup, Christoph Wirblich, and Matthias J. Schnell
Manuscripts from 2022
The Lack of Natural IgM Increases Susceptibility and Impairs Anti-Vi Polysaccharide IgG Responses in a Mouse Model of Typhoid, Akhil S. Alugupalli, Matthew P. Cravens, Justin A. Walker, Dania Gulandijany, Gregory S. Dickinson, Genevieve Lewis, Gudrun F. Debes, Dieter M. Schifferli, Andreas J. Bäumler, and Kishore R. Alugupalli
The Immune Synapses Reveal Aberrant Functions of CD8 T Cells During Chronic HIV Infection, Nadia Anikeeva, Maria Steblyanko, Leticia Kuri-Cervantes, Marcus Buggert, Michael R. Betts, and Yuri Sykulev
Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines., Valentina Ceglia, Sandra Zurawski, Monica Montes, Mitchell Kroll, Aurélie Bouteau, Zhiqing Wang, Jerome Ellis, Botond Z Igyártó, Yves Lévy, and Gerard Zurawski
Attenuation of Relapsing Fever Neuroborreliosis in Mice by IL-17A Blockade, Meihui Cheng, Jingwen Xu, Kaiyun Ding, Jing Zhang, Wei Lu, Jiansheng Liu, Jiahong Gao, Kishore R Alugupalli, and Hongqi Liu
Is Strongyloides Stercoralis Hyperinfection Induced by Gglucocorticoids a Result of Both Suppressed Host Immunity and Altered Parasite Genetics?, De'Broski R Herbert, Jonathan D C Stoltzfus, Heather L Rossi, and David Abraham
Intracellular Monitoring by Dendritic Cells - A New Way to Stay Informed - from a Simple Scavenger to an Active Gatherer, Christopher Herbst, Larry A Harshyne, and Botond Z Igyártó
"Don't Look Up" Your Science-Herd Immunity or Herd Mentality?, Botond Z Igyártó
A Single Dose of the Deactivated Rabies-Virus Vectored COVID-19 Vaccine, CORAVAX, Is Highly Efficacious and Alleviates Lung Inflammation in the Hamster Model, Drishya Kurup, Christoph Wirblich, Leila Zabihi Diba, Rachael Lambert, Megan Watson, Noor Shaikh, Holly Ramage, Charalambos Solomides, and Matthias J Schnell
Preprint Highlight: Vimentin Intermediate Filaments Organize Organellar ER Architecture in Response to Stress, Adriana Mantegazza
Interferon Partly Dictates a Divergent Transcriptional Response in Poxvirus-Infected and Bystander Inflammatory Monocytes, Carolina R Melo-Silva, Marisa I Roman, Cory J Knudson, Lingjuan Tang, Ren-Huan Xu, Michel Tassetto, Patrick Dolan, Raul Andino, and Luis J. Sigal
Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses, Sonia Ndeupen, Aurélie Bouteau, Christopher Herbst, Zhen Qin, Sonya Jacobsen, Nicholas E Powers, Zachary Hutchins, Drishya Kurup, Leila Zabihi Diba, Megan Watson, Holly Ramage, and Botond Z. Igyártó
Pre-exposure to mRNA-LNP Inhibits Adaptive Immune Responses and Alters Innate Immune Fitness in an Inheritable Fashion, Zhen Qin, Aurélie Bouteau, Christopher Herbst, and Botond Z. Igyártó
Arsenic Toxicity on Metabolism and Autophagy in Adipose and Muscle Tissues, Seung-Hyun Ro, Jiyoung Bae, Yura Jang, Jacob Myers, Soonkyu Chung, Jiujiu Yu, Sathish Kumar Natarajan, Rodrigo Franco, and Hyun-Seob Song
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells., Yung-Hsuan Wu, Shu-Ting Mo, I-Ting Chen, Fu-Yi Hsieh, Shie-Liang Hsieh, Jianke Zhang, and Ming-Zong Lai
Manuscripts from 2021
Development of a recombinant vaccine against human onchocerciasis., David Abraham, John Graham-Brown, Darrick Carter, Sean A. Gray, Jessica A. Hess, Benjamin L. Makepeace, and Sara Lustigman
Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs, Nadia Anikeeva, Sergey Panteleev, Nicholas W Mazzanti, Mizue Terai, Takami Sato, and Yuri Sykulev
Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing., Maria Ferez, Cory J. Knudson, Avital Lev, Eric B. Wong, Pedro Alves-Peixoto, Lingjuan Tang, Colby Stotesbury, and Luis J. Sigal
Cross Talk between ARF1 and RhoA Coordinates the Formation of Cytoskeletal Scaffolds during Chlamydia Infection, Adam Haines, Jordan Wesolowski, Nathan M Ryan, Tiago Monteiro-Brás, and Fabienne Paumet
Targeting human langerin promotes HIV-1 specific humoral immune responses., Jérôme Kervevan, Aurélie Bouteau, Juliane S Lanza, Adele Hammoudi, Sandra Zurawski, Mathieu Surenaud, Lydie Dieudonné, Marion Bonnet, Cécile Lefebvre, Hakim Hocini, Romain Marlin, Aurélie Guguin, Barbara Hersant, Oana Hermeziu, Elisabeth Menu, Christine Lacabaratz, Jean-Daniel Lelièvre, Gerard Zurawski, Véronique Godot, Sandrine Henri, Botond Z. Igyártó, Yves Levy, and Sylvain Cardinaud
Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection., Cory J Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J C Lin, Ying K Tam, Drew Weissman, Norbert Pardi, and Luis J. Sigal
Inactivated rabies virus vectored SARS-CoV-2 vaccine prevents disease in a Syrian hamster model., Drishya Kurup, Delphine C Malherbe, Christoph Wirblich, Rachael Lambert, Adam J Ronk, Leila Zabihi Diba, Alexander Bukreyev, and Matthias J. Schnell
Comparison of Lethal and Nonlethal Mouse Models of Orientia tsutsugamushi Infection Reveals T-Cell Population-Associated Cytokine Signatures Correlated with Lethality and Protection, Alison Luce-Fedrow, Suchismita Chattopadhyay, Teik-Chye Chan, Gregory Pearson, John B. Patton, and Allen L. Richards
A single dose of replication-competent VSV-vectored vaccine expressing SARS-CoV-2 S1 protects against virus replication in a hamster model of severe COVID-19., Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, and Alexander Bukreyev
Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells., Carolina R Melo-Silva, Pedro Alves-Peixoto, Natasha Heath, Lingjuan Tang, Brian Montoya, Cory J Knudson, Colby Stotesbury, Maria Ferez, Eric B. Wong, and Luis J. Sigal
The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory, Sonia Ndeupen, Zhen Qin, Sonya Jacobsen, Aurélie Bouteau, Henri Estanbouli, and Botond Z. Igyártó
A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue, Rama Devudu Puligedda, Fetweh H Al-Saleem, Christoph Wirblich, Chandana Devi Kattala, Marko Jović, Laura Geiszler, Himani Devabhaktuni, Giora Z Feuerstein, Matthias J. Schnell, Markus Sack, Lawrence L Livornese, and Scott K Dessain
Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice, Nathan M Ryan, Jessica A. Hess Ligas, Fernando Pardo-Manuel de Villena, Benjamin E Leiby, Ayako Shimada, Lei Yu, Amir Yarmahmoodi, Nikolai Petrovsky, Bin Zhan, Maria Elena Bottazzi, Benjamin L Makepeace, Sara Lustigman, and David Abraham
Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8+ T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation, Corinne J. Smith and Christopher M. Snyder
Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth., Lauren E. Springer, John B. Patton, Tingting Zhan, Arnold B. Rabson, Hsin-Ching Lin, Tim Manser, James B. Lok, Jessica A. Hess, and David Abraham
Dysregulated anti-viral innate immune cascade during aging., Colby Stotesbury and Luis J. Sigal
SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms, Christine Vazquez, Sydnie E Swanson, Seble G Negatu, Mark Dittmar, Jesse Miller, Holly Ramage, Sara Cherry, and Kellie A Jurado
Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion., Shunchuan Zhang, Lauren E Springer, Han-Zhi Rao, Renee G Espinosa Trethewy, Lindsey M Bishop, Meaghan H Hancock, Finn Grey, and Christopher M. Snyder
Manuscripts from 2020
Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19., Paolo Antonio Ascierto, Bernard Fox, Walter Urba, Ana Carrizosa Anderson, Michael B Atkins, Ernest C Borden, Julie Brahmer, Lisa H Butterfield, Alessandra Cesano, Daniel Chen, Tanja de Gruijl, Robert O Dillman, Charles G Drake, Leisha A Emens, Thomas F Gajewski, James L Gulley, F Stephen Hodi, Patrick Hwu, David Kaufman, Howard Kaufman, Michael Lotze, Douglas G McNeel, Kim Margolin, Francesco Marincola, Michael J Mastrangelo, Marcela V Maus, David R Parkinson, Pedro J Romero, Paul M Sondel, Stefani Spranger, Mario Sznol, George J Weiner, Jon M Wiggington, and Jeffrey S Weber
STXBP2-R190C Variant in a Patient With Neonatal Hemophagocytic Lymphohistiocytosis (HLH) and G6PD Deficiency Reveals a Critical Role of STXBP2 Domain 2 on Granule Exocytosis, Nathalia Benavides, Waldo A Spessott, Maria L Sanmillan, Marcelo Vargas, Mylynda S Livingston, Nissa Erickson, Tamara C Pozos, Margaret E McCormick, Emilia Scharrig, Yoav H Messinger, and Claudio G. Giraudo
Human t-cell leukemia virus type 1 and strongyloides stercoralis: Partners in pathogenesis, Adam Dykie, Tharaka Wijesinghe, Arnold B Rabson, Kiran Madugula, Christian Farinas, Sydney Wilson, David Abraham, and Pooja Jain
Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species, Julia Hunka, John T. Riley, and Gudrun F. Debes
Rabies virus-based COVID-19 vaccine CORAVAX™ induces high levels of neutralizing antibodies against SARS-CoV-2., Drishya Kurup, Christoph Wirblich, Holly Ramage, and Matthias J Schnell
Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides., Azad Mamedov, Nadezhda Vorobyeva, Ioanna Filimonova, Maria Zakharova, Ivan Kiselev, Vitalina Bashinskaya, Natalia Baulina, Alexey Boyko, Alexander Favorov, Olga Kulakova, Rustam Ziganshin, Ivan Smirnov, Alina Poroshina, Igor Shilovskiy, Musa Khaitov, Yuri Sykulev, Olga Favorova, Valentin Vlassov, Alexander Gabibov, and Alexey Belogurov
Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation., Colby Stotesbury, Eric B Wong, Lingjuan Tang, Brian Montoya, Cory J Knudson, Carolina R Melo-Silva, and Luis J Sigal
Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells., Qingtai Su, Aurélie Bouteau, Jacob Cardenas, Balaji Uthra, Yuanyaun Wang, Cynthia Smitherman, Jinghua Gu, and Botond Z. Igyártó
Manuscripts from 2019
TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3., John P. Dowling, Mohamed Alsabbagh, Christina Del Casale, Zheng-Gang Liu, and Jianke Zhang
Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans., Parakkal Jovvian George, Jessica A. Hess, Sonia Jain, John B. Patton, Tingting Zhan, Nancy Tricoche, Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, David Abraham, and Sara Lustigman
Rabies-based vaccine induces potent immune responses against Nipah virus., Rohan Keshwara, Thomas Shiels, Elena Postnikova, Drishya Kurup, Christoph Wirblich, Reed F. Johnson, and Matthias J. Schnell
Inactivated Rabies Virus-Based Ebola Vaccine Preserved by Vaporization Is Heat-Stable and Immunogenic Against Ebola and Protects Against Rabies Challenge., Drishya Kurup, Christine R. Fisher, Todd G. Smith, Tiago Abreu-Mota, Yong Yang, Felix R. Jackson, Nadia Gallardo-Romero, Richard Franka, Victor Bronshtein, and Matthias J. Schnell
Incorporating B cell activating factor (BAFF) into the membrane of rabies virus (RABV) particles improves the speed and magnitude of vaccine-induced antibody responses., Joseph R Plummer and James P McGettigan
From Vaccine Vector to Oncomodulation: Understanding the Complex Interplay between CMV and Cancer., Nicole A. Wilski and Christopher M. Snyder
Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy., Eric B. Wong, Brian Montoya, Maria Ferez, Colby Stotesbury, and Luis J. Sigal
Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node., Eric B. Wong, Brian Montoya, Colby Stotesbury, Maria Ferez, Ren-Huan Xu, and Luis J. Sigal
Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response., Yi Yang, Thea L. Willis, Robert W. Button, Conor J. Strang, Yuhua Fu, Xue Wen, Portia R.C. Grayson, Tracey Evans, Rebecca J. Sipthorpe, Sheridan L. Roberts, Bing Hu, Jianke Zhang, Boxun Lu, and Shouqing Luo
RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development., Xuhua Zhang, John P. Dowling, and Jianke Zhang
Manuscripts from 2018
Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever., Tiago Abreu-Mota, Katie R. Hagen, Kurt Cooper, Peter B. Jahrling, Gene Tan, Christoph Wirblich, Reed F. Johnson, and Matthias J. Schnell
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease., Marcus Buggert, Son Nguyen, Laura M. McLane, Maria Steblyanko, Nadia Anikeeva, Dominic Paquin-Proulx, Perla M Del Rio Estrada, Yuria Ablanedo-Terrazas, Kajsa Noyan, Morgan A. Reuter, Korey Demers, Johan K. Sandberg, Michael A. Eller, Hendrik Streeck, Marianne Jansson, Piotr Nowak, Anders Sönnerborg, David H. Canaday, Ali Naji, E. John Wherry, Merlin L. Robb, Steven G Deeks, Gustavo Reyes-Teran, Yuri Sykulev, Annika C. Karlsson, and Michael R. Betts
Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1, Sandra M. Cardona, Sangwon V. Kim, Kaira A. Church, Vanessa O. Torres, Ian A. Cleary, Andrew S. Mendiola, Stephen P. Saville, Stephanie S. Watowich, Jan Parker-Thornburg, Alejandro Soto-Ospina, Pedronel Araque, Richard M. Ransohoff, and Astrid E. Cardona
PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors., Dongshi Chen, Jingshan Tong, Liheng Yang, Liang Wei, Donna B. Stolz, Jian Yu, Jianke Zhang, and Lin Zhang
CD8+ T-cell responses in vaccination: Reconsidering targets and function in the context of chronic antigen stimulation, Gabriela L. Cosma and Laurence Eisenlohr
A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding., Bruno Hernáez, Juan Manuel Alonso-Lobo, Imma Montanuy, Cornelius Fischer, Sascha Sauer, Luis J. Sigal, Noemí Sevilla, and Antonio Alcamí
Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections., Isaac J. Jensen, Christina S. Winborn, Micaela G. Fosdick, Peng Shao, Mikaela M. Tremblay, Qiang Shan, Sandeep Kumar Tripathy, Christopher M. Snyder, Hai-Hui Xue, Thomas S. Griffith, Jon C. Houtman, and Vladimir P. Badovinac
Onchocerca volvulus: The Road from Basic Biology to a Vaccine., Sara Lustigman, Benjamin L. Makepeace, Thomas R. Klei, Simon A. Babayan, Peter Hotez, David Abraham, and Maria Elena Bottazzi
Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons., Margaret A. MacGibeny, Orkide O. Koyuncu, Christoph Wirblich, Matthias J. Schnell, and Lynn W. Enquist
Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum., John B. Patton, Sasisekhar Bennuru, Mark L. Eberhard, Jessica A. Hess Ligas, April R. Torigian, Sara Lustigman, Thomas B. Nutman, and David Abraham
Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease., Donna L. Perry, Louis M. Huzella, John G. Bernbaum, Michael R. Holbrook, Peter B. Jahrling, Katie R. Hagen, Matthias J. Schnell, and Reed F. Johnson
With some risk-taking and luck: A veterinarian's adventures in viral immunology., Luis J. Sigal
Manuscripts from 2017
Metabolite profiling of infection-associated metabolic markers of onchocerciasis., Sasisekhar Bennuru, Sara Lustigman, David Abraham, and Thomas B. Nutman
APRIL:TACI axis is dispensable for the immune response to rabies vaccination., Shannon L. Haley, Evgeni P. Tzvetkov, Andrew G. Lytle, Kishore R. Alugupalli, Joseph R. Plummer, and James P. McGettigan
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions., Alvaro Teijeira, Morgan C. Hunter, Erica Russo, Steven T Proulx, Thomas Frei, Gudrun F. Debes, Marc Coles, Ignacio Melero, Michael Detmar, Ana Rouzaut, and Cornelia Halin
Differentiation and Protective Capacity of Virus-Specific CD8, Vesselin T. Tomov, Olesya Palko, Chi Wai Lau, Ajinkya Pattekar, Yuhang Sun, Ralitza Tacheva, Bertram Bengsch, Sasikanth Manne, Gabriela L. Cosma, Laurence C. Eisenlohr, Timothy J. Nice, Herbert W. Virgin, and E. John Wherry
The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees?, Peter D. Walsh, Drishya Kurup, Dana L. Hasselschwert, Christoph Wirblich, Jason E. Goetzmann, and Matthias J. Schnell
Taking control: reorganization of the host cytoskeleton by Chlamydia., Jordan Wesolowski and Fabienne Paumet
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning., Jordan Wesolowski, Mary M. Weber, Agata Nawrotek, Cheryl A. Dooley, Mike Calderon, Claudette M. St Croix, Ted Hackstadt, Jacqueline Cherfils, and Fabienne Paumet
Manuscripts from 2016
Evaluating frequency and quality of pathogen-specific T cells., Nadia Anikeeva, Dolores Grosso, , and Yuri Sykulev
Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection., Sridhar Arumugam, Junfei Wei, Zhuyun Liu, David Abraham, Aaron Bell, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Sara Lustigman, and Thomas R Klei
YY1 Is Required for Germinal Center B Cell Development., Anupam Banerjee, Vishal Sindhava, Raja Vuyyuru, Vibha Jha, Suchita Hodewadekar, Tim Manser, and Michael L Atchison
Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation., John Bertin, Peter J. Gough, Jianke Zhang, John P. Dowling, and Yubo Cai
IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity., Phillip P. Domeier, Sathi Babu Chodisetti, Chetna Soni, Stephanie L. Schell, Melinda J. Elias, Eric B. Wong, Timothy K. Cooper, Daisuke Kitamura, and Ziaur S.M. Rahman
The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice., Jessica A. Hess Ligas, Bin Zhan, April R. Torigian, John B. Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J. Hotez, Thomas R. Klei, Sara Lustigman, and David Abraham
