A Rare Case of Diffuse Alveolar Hemorrhage Secondary to Dabigatran Successfully Treated with Extracorporeal Membrane Oxygenation
C. Hutchinson, F. M. West, and H. Hirose
Dabigatran, a direct thrombin inhibitor, is used for stroke risk reduction in non-valvular atrial fibrillation and for treatment and prevention of venous thromboembolism. Minor side effects include indigestion and stomach pain. Major life threatening bleeding occurs in up to 2% of patients and is largely attributed to gastrointestinal hemorrhage. Here, we describe a case of a dabigatran related diffuse alveolar hemorrhage (DAH) treated successfully with extracorporeal membrane oxygenation.
Frederick B. Peng and Sharon Li, MD
- Prescription drug abuse is on the rise. According to the Philadelphia Department of Health data in 2017, up to 26% of adults may be using benzodiazepines and/or opioids (Table 1).
- 12% or 1/8 Philadelphians are estimated to be current benzodiazepine users and have taken one in the last 7 days. Benzodiazepine use is most common among people with household incomes below $25,000 and among the 45-54 years old age group (17.7%) .
- Most current users (84%) obtain benzodiazepines from health care providers . However, with new policies to closely monitor controlled substances, those with dependence on benzodiazepines may turn to alternative sources (such as black market vendors) to obtain the drug.
- Street-obtained versions may be substituted or mixed with alternative products to maximize profits for vendors. Unsuspecting users can be subject to life-threatening side effects.
- •To clinicians caring for these patients, the composition of benzodiazepines obtained outside of a pharmacy may not easily be identifiable, making treating intoxications a challenge.
Gretchen A. Diemer, MD and Emily Stewart, MD
Orientation is a whirlwind of regulations, reminders, rules and usually some social outlets. Very little of it helps new interns foster and celebrate their blossoming professional identity. The book club combats the hidden curriculum emphasizing regulations and policies by nurturing the growing sense of whom they are as physicians, actively placing value on the idea that they are developing a professional identity.
Reduction of Central line Associated Bloodstream Infections in an Urban 40 bed, Level III Neonatal Intensive Care Unit when new practices were implemented
Roberta Glenn, BSMT (ASCP) CIC
- Central line-associated bloodstream infection (CLABSI) in the neonatal population is a major source of morbidity and mortality.
- The disruption of skin and mucus membranes by the use of invasive devices contributes to the susceptibility of this population.
- In our Neonatal Intensive Care Unit (NICU), the CLABSI rate was continually increasing.
- It became evident that new practice guidelines were necessary to reduce the CLABSI rate in this vulnerable population.
Poster presented at: APIC 2017 in Portland Oregon, United States.
Shashank Jain, MD; Priya Rajagopalan, MD; Mitul Kanzaria, MD; and Meir Mazuz, MD
- Acute myocardial infarction (MI) in young adults can present a diagnostic and therapeutic challenge
- Kawasaki disease (KD) is a vasculitis of unknown etiology that occurs in infancy and childhood
- Coronary artery aneurysms (CAA) are the most serious complication of untreated KD seen in upto 25% of patients
- Thrombosis of these CAA or coronary stenosis can present as MI in less than 2% of cases which mainly occur in the 1st year of disease onset
- Late presentations in adult life is extremely rare
Drew Kotler, MD; Mital Shah, MD; Sheela S. Reddy, MD; Jonathan M. Fenkel, MD; John Liantonio, MD; and Dina Halegoua-De Marzio, MD
● Palliative Care services are often underutilized in patients with End-Stage Liver Disease (ESLD) and often only initiated at the end of life
● The Palliative Performance Score (PPS) is an important tool used in Palliative Care to assess functional status
● PPS has five functional dimensions: ambulation, activity level and evidence of disease, self-care, oral intake, and level of consciousness
● The aim of this study is to determine if there is a correlation between Model for End-Stage Liver Disease (MELD) score and PPS in ESLD patients
● MELD is used to predict mortality and to prioritize liver transplant allocation in ESLD patients
Strategic approach of an urban 900-bed academic medical center to combat Clostridium difficile infection transmission using staff engagement
Courtney Mitchell, MPH and Kelly Zabriskie, CIC
- Clostridium difficile infection (CDI) caused nearly 500,000 illnesses with 29,000 deaths in the United States
- Preventing hospital-associated Clostridium difficile infection (HA-CDI) is crucial to modern healthcare systems for reducing mortality, healthcare costs and length of stay
- There are multiple risk factors for CDI transmission in healthcare settings:
- Failure to comply with hand hygiene
- Ineffective equipment and surface cleaning
- Diagnosis delays
Poster presented at: APIC 2017 in Portland Oregon, United States.
Joseph Spataro; Richard Denicola; Drew Kotler, MD; and Albert Lee, MD
- An estimated 28% of eligible US adults have never been screened for colorectal cancer (CRC) 2
- Fecal Immunochemical Testing (FIT) offers an acceptable non-invasive screening option
- An estimated 56% of patients at our internal medicine clinic have not had colorectal cancer screening and alternatives to colonoscopy were seldom promoted
Poster presented at: Pennsylvania Society of Gastroenterology (PSG) Annual Scientific Meeting 2017 at Nemacolin Woodlands Resort, Farmington, Pennsylvania, United States of America.
Joseph Spataro, Mazen Tolaymat, Charles Kistler, Michael Jacobs, Jeffrey Fitch, and Monjur Ahmed
- Clinical manifestations of choledocholithiasis include biliary colic, obstructive jaundice, pancreatitis, and acute cholangitis
- Secondary common bile duct (CBD) stones are common when the gallbladder is intact or after recent cholecystectomy (CCY) whereas recurrent stones develop >3 years after surgery1,2
- Patients with retained CBD stones after CCY may be asymptomatic for years and there is limited data on their pattern of presentation
- Despite known predisposing conditions and risk factors for recurrent biliary disease, the role of intraoperative cholangiography (IOC) during CCY remains controversial
Poster presented at: World Congress of Gastroenterology at ACG 2017 in Orlando Florida, United States.
Donald M. Friedman, MD and Vic Compher, MSS, LCSW
Poster presented at International Conference of Physician Health in Boston Massachusetts.
Supplementary handout with definitions and extensive bibliography available at bottom of page.
Film is basis for poster: Portraits of Professional Caregivers-Their Passion. Their Pain (click on picture to view movie trailer)
Quotes about movie from IMDB
1. Become more aware of what secondary trauma is and its prevalence in health care professionals
2. Recognize the importance of personal wellness and intentional self-care by physicians and other allied professionals
3. Encourage the development of medical systems in the formation of effective peer support structures
The documentary filmmaker, Vic Compher, a former administrator, supervisor and social worker in the Department of Human Services in Philadelphia, realized the presence of secondary trauma in professionals who rescue, assist and/or treat injured, traumatized or physically ill patients. His film, “Portraits of Professional Caregivers – Their Passion, Their Pain,” contains narrative interviews with a broad spectrum of professional empathetic caregivers who describe the stressful effects of their work and how those stresses affect them emotionally and functionally. The purpose of these stories is to promote awareness of secondary trauma/compassion fatigue and how it can be toxic and lead to burnout, promote provider self-care and emphasize the need for an organizational structure that provides support and healing for the medical staff.
Our poster will provide a colorful chart with the statistics of physician burnout and a display of the statistics of secondary trauma in allied professions. The poster will also include definitions of secondary trauma/compassion fatigue, burnout and compassion satisfaction. There will be dramatic still shots from the film depicting professional narratives, self-care in action and group peer debriefing/support sessions. Handouts will include a bibliography of current research, definitions and symptoms of secondary trauma and burnout, illustrations of compassion satisfaction, and examples of organizational structures that provide emotional support and healing for medical staff.
Secondary trauma is prevalent among a wide variety of professional caregivers and can lead to poor performance, dissatisfaction with work and burnout. Provider self-care and institutional support of the caregiver are crucial for promoting compassion satisfaction and resiliency.
Secondary trauma is a recognized occupational hazard of professional caregivers but can be countered by self-awareness, self-care and institutional support.
Anthony J. Frisby, PhD; Steven Herrine, MD; and Deborah Ziring, MD
The Sidney Kimmel Medical College (SKMC) at Thomas Jefferson University (TJU) is creating a new medical curriculum (JeffMD), in which more learning will take place in small groups and individual activities.
In their small groups, students will focus on core case studies that will become increasingly complex, each building on the prior phase of the curriculum.
Rhea E. Powell, MD, MPH; Jeffrey Henstenburg, BS; Grace Cooper, BA; Judd Hollander, MD; and Kristin L. Rising, MD, MS
- Telehealth (TH) is an innovative model of care delivery with potential to provide more patient-centered healthcare, allowing patients to receive care when and where is most convenient.
- To date, little is known about patient perceptions of receiving care with the use of TH video visits.
Megan K. Ford, MD; Alana B. Kekevian, DO; Charalambos C. Solomides, MD; and John R. Cohn, MD, FACAAI
- Follicular bronchiolitis (FB) in patients with common variable immune deficiency (CVID) is rarely described and knowledge is based on case reports, case series, and studies on the individual disease entities.1-5
- FB is a granulomatous-lymphocytic interstitial lung disease (GLILD). GLILD is a group of non-infectious lung diseases which also includes lymphocytic interstitial pneumonia, granulomatous disease, and lymphoid hyperplasia.6,7
- FB is caused by an external stimulus or abnormal immune response that incites lymphoid hyperplasia.8
- The etiology of FB is idiopathic or associated with collagen vascular disorders (e.g., Sjogrens, rheumatoid arthritis), hypersensitivity reactions, acquired immunodeficiencies (typically HIV), and less commonly, primary immunodeficiencies.9,10 In case reports, FB has also been linked to primary ciliary dyskinesia, multicentric Castleman’s disease, primary tuberculosis, and eosinophilia with elevated IgE.11-14
- The differential diagnosis of FB includes other types of GLILD, low grade bronchus associated lymphoid tissue lymphoma, and sarcoidosis.1
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