Whole-Genome Bisulfite Sequencing of Cell-free DNAs Identified Molecular Contributors to Racial Survival Difference in Advanced-Stage Triple-Negative Breast Cancer Patients

Authors

Chun Wang, Thomas Jefferson UniversityFollow
Steven Manobianco, Thomas Jefferson UniversityFollow
Maria Hafez, Thomas Jefferson UniversityFollow
Mouadh Barbirou, Thomas Jefferson UniversityFollow
Grace Qiu, Thomas Jefferson UniversityFollow
Ashley Wetzel, Thomas Jefferson UniversityFollow
David Baek, Thomas Jefferson UniversityFollow
Hushan Yang, Thomas Jefferson UniversityFollow
Maysa Abu-Khalaf, Thomas Jefferson UniversityFollow

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Description

Background

• Black women are twice as likely to be diagnosed with triple-negative breast cancer (TNBC) as compared to White women.
• The impact of genomic and molecular factors on the racial disparity in TNBC survival remains understudied.
• Liquid biopsy has yet to be explored in the context of racial survival disparities in TNBC.

Publication Date

6-2-2025

Keywords

breast cancer, cancer genomics, precision medicine, translational science, cancer disparities

Disciplines

Medicine and Health Sciences | Oncology

Comments

Presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.

Recommended Citation

Wang, Chun; Manobianco, Steven; Hafez, Maria; Barbirou, Mouadh; Qiu, Grace; Wetzel, Ashley; Baek, David; Yang, Hushan; and Abu-Khalaf, Maysa, "Whole-Genome Bisulfite Sequencing of Cell-free DNAs Identified Molecular Contributors to Racial Survival Difference in Advanced-Stage Triple-Negative Breast Cancer Patients" (2025). Department of Medical Oncology Posters. 24.
https://jdc.jefferson.edu/medoncposters/24