ACTH-dependent Cushing’s syndrome results from excessive ACTH secretion from a pituitary gland adenoma (Cushing’s disease) in 80% of cases. Much less commonly, ectopic ACTH production occurs outside the pituitary gland, with the majority of those cases caused by bronchial carcinoids. A small number are due to excessive ACTH secretion by a pheochromocytoma.
Recommended CitationGerber, MD, Susan; Kenyon, MD, PhD, Lawrence C.; McCullen, Mary Kate; and Jabbour, MD, FACP, FACE, Serge, "Ectopic Cushing's Syndrome from ACTH-Producing Pheochromocytoma" (2013). Department of Medicine Faculty Papers. Paper 90.