Article Title

Neuroleptic Malignant Syndrome, with Attention to Its Occurrence with Atypical Antipsychotic Medication: A Review

Authors

Sarah Guzofski M.D. (PGY2)Follow
Ruben Peralta M.D.

Abstract

The neuroleptic malignant syndrome (NMS) is an idiopathic, life-threatening reaction to antipsychotic medication. NMS was traditionally attributed to potent dopamine antagonism of typical antipsychotics, but cases of NMS have now been reported for each of the newer antipsychotics. When NMS is caused by a newer, atypical antipsychotic the presentation differs somewhat; fever, rigidity, and, possibly, death may be less frequent. Diagnostic features, predisposing factors, and treatment are discussed, as is the important matter of reinstituting antipsychotic treatment.

Recommended Citation

Guzofski, Sarah M.D. (PGY2) and Peralta, Ruben M.D. (2006) "Neuroleptic Malignant Syndrome, with Attention to Its Occurrence with Atypical Antipsychotic Medication: A Review," Jefferson Journal of Psychiatry: Vol. 20: Iss. 1, Article 7.
DOI: https://doi.org/10.29046/JJP.020.1.009
Available at: https://jdc.jefferson.edu/jeffjpsychiatry/vol20/iss1/7