Carbamazepine has been proven to be efficacious in some patients with affective disorders, notably those who have not responded well to lithium carbonate or neuroleptics (1,2,3) . For those who have responded poorly to either regimen, however, there have been no effective pharmacotherapies until recently, when case reports have suggested a possible synergistic action between lithium carbonate and carbamazepine (4,5,6). The following case report supports this hypothesis.
Dorn, M.D., John Matt
"Possible Synergistic Action Between Carbamazepine and Lithium Carbonate in the Treatment of a Manic Patient.,"
Jefferson Journal of Psychiatry: Vol. 2
, Article 8.
Available at: https://jdc.jefferson.edu/jeffjpsychiatry/vol2/iss1/8