Study objective: This study sought to assess the predictive value of H2FPEF score in patients with COVID-19.
Design: Retrospective study.
Setting: Rush University Medical Center.
Participants: A total of 1682 patients had an echocardiogram in the year preceding their COVID-19 admission with a preserved ejection fraction (≥50%). A total of 156 patients met inclusion criteria. Interventions: Patients were divided into H2FPEF into low (0–2), intermediate (3–5), and high (6–9) score H2FPEF groups and outcomes were compared.
Main outcome measures: Adjusted multivariable logistic regression models evaluated the association between H2FPEF score group and a composite outcome for severe COVID-19 infection consisting of (1) 60-day mortality or illness requiring (2) intensive care unit, (3) intubation, or (4) non-invasive positive pressure ventilation.
Results: High H2FPEF scores were at increased risk for severe COVID-19 infection when compared intermediate to H2FPEF score groups (OR 2.18 [CI: 1.01–4.80]; p = 0.049) and low H2FPEF score groups (OR 2.99 [CI: 1.22–7.61]; p < 0.05). There was no difference in outcome between intermediate H2FPEF scores (OR 1.34 [CI: 0.59–3.16]; p = 0.489) and low H2FPEF score.
Conclusions: Patients with a high H2FPEF score were at increased risk for severe COVID-19 infection when compared to patients with an intermediate or low H2FPEF score regardless of regardless of coronary artery disease and chronic kidney disease.
Patel, Priya; Ruge, Max; Gomez, Joanne Michelle D.; du Fay de Lavallaz, Jeanne; Rao, Anupama; Williams, Kim A.; Volgman, Annabelle Santos; Costanzo, Maria Rosa R.; Suboc, Tisha; and Marinescu, Karolina, "Prognostic Value of H2FPEF Score in COVID-19" (2022). Division of Internal Medicine Faculty Papers & Presentations. Paper 62.
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This article is the author's final published version in American Heart Journal Plus: Cardiology Research and Practice, Volume 13, January 2022, Article number 100111.
The published version is available at https://doi.org/10.1016/j.ahjo.2022.100111. Copyright © 2022 The Authors. Published by Elsevier Inc.