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Submissions from 2024

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Investigating Clot-Flow Interactions by Integrating Intravital Imaging with in Silico Modeling for Analysis of Flow, Transport, and Hemodynamic Forces, Chayut Teeraratkul, Maurizio Tomaiuolo, Timothy Stalker, and Debanjan Mukherjee

Submissions from 2023

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Activation of Coagulation and Proinflammatory Pathways in Thrombosis with Thrombocytopenia Syndrome and Following COVID-19 Vaccination, Malika Aid, Kathryn E. Stephenson, Ai-Ris Y. Collier, Joseph P. Nkolola, James V. Michael, Steven E. McKenzie, and Dan H. Barouch

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PET Imaging of Microglia Using PBR28suv Determines Therapeutic Efficacy of Autologous Bone Marrow Mononuclear Cells Therapy in Traumatic Brain Injury, Supinder S Bedi, Michael C Scott, Max A Skibber, Akshita Kumar, Henry W Caplan, Hasen Xue, David Sequeira, Alison L Speer, Fanni Cardenas, Franciska Gudenkauf, Karen Uray, Amit K. Srivastava, Alan R Prossin, and Charles S Cox

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Glutamate Receptor Dysregulation and Platelet Glutamate Dynamics in Alzheimer's and Parkinson's Diseases: Insights into Current Medications, Deepa Gautam, Ulhas Naik, Meghna Naik, Santosh Yadav, Rameshwar Nath Chaurasia, and Debabrata Dash

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The Function of ASK1 in Sepsis and Stress-Induced Disorders, John Kostyak, Steven McKenzie, and Ulhas Naik

Fluorescent Peptide for Detecting Factor XIIIa Activity and Fibrin in Whole Blood Clots Forming Under Flow, Yue Liu, Jennifer Crossen, Timothy J. Stalker, and Scott L. Diamond

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Species Differences in Platelet Protease-Activated Receptors, Stephanie A Renna, Steven E. McKenzie, and James V. Michael

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Illustrated Abstracts of the 5th EUPLAN International Conference, Alexandra Yakusheva, Alexandre Slater, Bernard Payrastre, Cédric Garcia, Giorgia D'Italia, Harriet Allan, Judith M. E. M. Cosemans, Matthew Harper, Meinrad Gawaz, Paul Armstrong, Sara Troitiño, Silvia Maria Grazia Trivigno, Ulhas P. Naik, and Yotis A. Senis

Submissions from 2022

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G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1., Kate Downes, Xuefei Zhao, Nicholas S Gleadall, Harriet McKinney, Carly Kempster, Joana Batista, Patrick L Thomas, Matthew Cooper, James V Michael, Roman Kreuzhuber, Katherine Wedderburn, Kathryn Waller, Bianca Varney, Hippolyte Verdier, Neline Kriek, Sofie E Ashford, Kathleen E Stirrups, Joanne L Dunster, Steven E McKenzie, Willem H Ouwehand, Jonathan M Gibbins, Jing Yang, William J Astle, and Peisong Ma

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Defective RAB31-mediated Megakaryocytic Early Endosomal Trafficking of VWF, EGFR, and M6PR in RUNX1 Deficiency, Gauthami Jalagadugula, Guangfen Mao, Lawrence E Goldfinger, Jeremy Wurtzel, Fabiola Del Carpio-Cano, Michele P Lambert, Brian Estevez, Deborah L French, Mortimer Poncz, and A Koneti Rao

Submissions from 2021

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PCTP contributes to human platelet activation by enhancing dense granule secretion, Shaji Abraham, Lin Ma, Xianguo Kong, Shayan Askari, Leonard Edelstein, and Steven McKenzie

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Predicting risk factors for thromboembolic complications in patients with sickle cell anaemia - lessons learned for prophylaxis, Salam Alkindi, Anwaar R Al-Ghadani, Samah R Al-Zeheimi, Said Y Alkindi, Naglaa Fawaz, Samir K. Ballas, and Anil V Pathare

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Opioids and Sickle Cell Disease: From Opium to the Opioid Epidemic., Samir K. Ballas

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Opioids are not a major cause of death of patients with sickle cell disease., Samir K. Ballas

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Voxelotor Modulates the Analgesic Effect of Certain Opioids., Samir K. Ballas

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Determinants of the Outcome of the Transition of Children with Sickle Cell Disease to Adult Programs., Samir K. Ballas, Gaye Riddick-Burden, and Elisabeth Congdon-Martin

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Platelets as drivers of ischemia/reperfusion injury after stroke., Noor F Shaik, Raymond F Regan, and Ulhas P Naik

Submissions from 2020

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Predictors of impending acute chest syndrome in patients with sickle cell anaemia., Salam Alkindi, Ikhlas Al-Busaidi, Bushra Al-Salami, Samir Raniga, Anil Pathare, and Samir K. Ballas

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The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease., Samir K Ballas

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How I Treat Acute and Persistent Sickle Cell Pain., Samir K. Ballas

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Review/overview of pain in sickle cell disease., Samir K. Ballas and Deepika S. Darbari

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GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets., Xi Chen, Shuchi Gupta, Matthew Cooper, Daniel DeHelian, Xuefei Zhao, Meghna U. Naik, Jeremy G.T. Wurtzel, Timothy J. Stalker, Lawrence E. Goldfinger, Jeffrey Benovic, Lawrence F. Brass, Steven E. McKenzie, Ulhas P. Naik, and Peisong Ma

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The vaso-occlusive pain crisis in sickle cell disease: Definition, pathophysiology, and management., Deepika S. Darbari, Vivien A. Sheehan, and Samir K. Ballas

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Bayesian modelling of high-throughput sequencing assays with malacoda., Andrew R Ghazi, Xianguo Kong, Ed S Chen, Leonard C Edelstein, and Chad A Shaw

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Transcutaneous electrical nerve stimulation (TENS) for pain management in sickle cell disease., Sudipta Pal, Ruchita Dixit, Soe Moe, Myron Anthony Godinho, Adinegara Bl Abas, Samir K. Ballas, Shanker Ram, and Uduman Ali M. Yousuf

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Menopause in Brazilian women with sickle cell anemia with and without hydroxyurea therapy., Ana Mach Queiroz, Clarisse Lopes de Castro Lobo, and Samir K. Ballas

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Case Series and Review of Hematological and Non-Hematological Malignancies in Aging Patients with Sickle Cell Disease in the Hydroxyurea Era., Sanaa Rizk, David J. Axelrod, Rasaq Olaosebikan, and Samir K. Ballas

Submissions from 2019

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Pharmacological interventions for painful sickle cell vaso-occlusive crises in adults., Tess E. Cooper, Ian R. Hambleton, Samir K. Ballas, Brydee A. Johnston, and Philip J. Wiffen

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Survival Probability in Patients with Sickle Cell Anemia Using the Competitive Risk Statistical Model., Emilia Matos do Nascimento, Clarisse Lopes de Castro Lobo, Basilio de Bragança Pereira, and Samir K. Ballas

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GPVI inhibitor as antitumor gateway drug., Lawrence E. Goldfinger

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Horizontal RNA transfer goes deep: platelet consumption and microRNA utilization by vascular smooth muscle cells., Lawrence E. Goldfinger and Leonard C. Edelstein

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Functionalization of CD36 Cardiovascular Disease and Expression Associated Variants by Interdisciplinary High Throughput Analysis., Namrata Madan, Andrew R. Ghazi, Xianguo Kong, Edward S. Chen, Chad A. Shaw, and Leonard C. Edelstein

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Treatment of dental complications in sickle cell disease., Priti Mulimani, Samir K. Ballas, Adinegara Bl Abas, and Laxminarayan Karanth

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Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen., Claire Simonneau, Junning Yang, Xianguo Kong, Robert Kilker, Leonard Edelstein, Paolo Fortina, Eric R. Londin, and Arie Horowitz

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Murine MPDZ-linked hydrocephalus is caused by hyperpermeability of the choroid plexus., Junning Yang, Claire Simonneau, Robert Kilker, Laura Oakley, Matthew D. Byrne, Zuzana Nichtova, Ioana Stefanescu, Fnu Pardeep-Kumar, Sushil Tripathi, Eric Londin, Pascale Saugier-Veber, Belinda Willard, Mathew Thakur, Stephen Pickup, Hiroshi Ishikawa, Horst Schroten, Richard Smeyne, and Arie Horowitz

Submissions from 2018

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Comorbidities in aging patients with sickle cell disease., Samir K. Ballas

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Sickle cell disease: Classification of clinical complications and approaches to preventive and therapeutic management., Samir K. Ballas

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Blood rheological abnormalities in sickle cell anemia., Philippe Connes, Céline Renoux, Marc Romana, Manouk Abkarian, Philippe Joly, Cyril Martin, Marie-Dominique Hardy-Dessources, and Samir K. Ballas

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Mortality in children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil., Clarisse Lopes de Castro Lobo, Emilia Matos do Nascimento, Leonardo José Carvalho de Jesus, Thiago Gotelip de Freitas, Jocemir Ronaldo Lugon, and Samir K. Ballas

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Drugs for preventing red blood cell dehydration in people with sickle cell disease., Srikanth Nagalla and Samir K. Ballas

Submissions from 2017

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Beyond the transition of adolescents and young adults with sickle cell disease to adult care: Role of geography., Nina Anderson, James R. Eckman, and Samir K. Ballas

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The role of platelet microvesicles in intercellular communication., Leonard C. Edelstein

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Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP., Xianguo Kong, Lukas M. Simon, Michael Holinstat, Chad A. Shaw, Paul F. Bray, and Leonard C. Edelstein

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Transcutaneous electrical nerve stimulation (TENS) for pain management in sickle cell disease, Sudipta Pal, Ruchita Dixit, Soe Moe, Myron A. Godinho, Adinegara B.L. Abas, Samir K. Ballas, Shanker Ram, and Uduman A.M. Yousuf

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Obesity-induced Endoplasmic Reticulum Stress Causes Lung Endothelial Dysfunction and Promotes Acute Lung Injury, Dilip Shah, Freddy Romero, Zhi Guo, Jianxin Sun, Jonathan C. Li, Caleb Kallen, Ulhas P. Naik, and Ross Summer

Submissions from 2016

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Conjugate Haemophilus influenzae type b vaccines for sickle cell disease., Slimane Allali, Martin Chalumeau, Odile Launay, Samir K. Ballas, and Mariane de Montalembert

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Safety and efficacy of blood exchange transfusion for priapism complicating sickle cell disease., Samir K. Ballas and David Lyon

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Pharmacological interventions for painful sickle cell vaso-occlusive crises in adults, Tess E. Cooper, Ian R. Hambleton, Samir K. Ballas, and Philip J. Wiffen

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A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease., Li Liu, Alexander Pertsemlidis, Liang-Hao Ding, Michael D Story, Martin H Steinberg, Paola Sebastiani, Carolyn Hoppe, Samir K. Ballas, and Betty S Pace

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Treatment of dental complications in sickle cell disease., Priti Mulimani, Samir K. Ballas, Adinegara B L Abas, and Laxminarayan Karanth

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Trends in survival of chronic lymphocytic leukemia patients in Germany and the USA in the first decade of the twenty-first century., Dianne Pulte, Felipe A Castro, Lina Jansen, Sabine Luttmann, Bernd Holleczek, Alice Nennecke, Meike Ressing, Alexander Katalinic, and Hermann Brenner

Submissions from 2015

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Clinical Utility of Lactate Dehydrogenase in Determining the Severity of Hemolysis in Sickle Cell Anemia., Samir K. Ballas

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The paradox of the serrated sickle erythrocyte: The importance of the red blood cell membrane topography., Samir K. Ballas and Philippe Connes

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Morphine for the treatment of pain in sickle cell disease., Mihir Gupta, Lilian Msambichaka, Samir K. Ballas, and Kalpna Gupta

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Risk Factors of Pulmonary Hypertension in Brazilian Patients with Sickle Cell Anemia., Clarisse Lopes de Castro Lobo, Emilia Matos do Nascimento, Renato Abelha, Ana Maria Mach Queiroz, Philippe Connes, Gilberto Perez Cardoso, and Samir K. Ballas

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Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus., Martina Mijušković, Yi-Fan Chou, Vered Gigi, Cory R Lindsay, Olga Shestova, Susanna M Lewis, and David B Roth

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Emerging drugs for sickle cell anemia., Priya C Singh and Samir K. Ballas

Submissions from 2014

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Primary stroke in a woman with sickle cell anemia responsive to hydroxyurea therapy., Samir K. Ballas, Ubaldo E. Martinez-Outshoorn, and Michael P. Savage

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Deferiprone versus Deferoxamine in Sickle Cell Disease: Results from a 5-year long-term Italian multi-center randomized clinical trial., Giusi Calvaruso, Angela Vitrano, Rosario Di Maggio, Samir K. Ballas, Martin H Steinberg, Paolo Rigano, Massimiliano Sacco, Paul Telfer, Disma Renda, Rita Barone, and Aurelio Maggio

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MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression., Raúl Teruel Montoya, Xianguo Kong, Shaji Abraham, Lin Ma, Satya P Kunapuli, Michael Holinstat, Chad A Shaw, Steven E. McKenzie, Leonard Edelstein, and Paul Bray

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Survival of adults with acute lymphoblastic leukemia in Germany and the United States., Dianne Pulte, Lina Jansen, Adam Gondos, Alexander Katalinic, Benjamin Barnes, Meike Ressing, Bernd Holleczek, Andrea Eberle, Hermann Brenner, and GEKID Cancer Survival Working Group

Submissions from 2013

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Transfusion medicine illustrated. The first Cardeza donor center: attracting donors who do not wsh to see blood., Samir K. Ballas

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Neuropathy, neuropathic pain, and sickle cell disease., Samir K. Ballas and Deepika S Darbari

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The complex transcriptional landscape of the anucleate human platelet., Paul F. Bray, Steven E. McKenzie, Leonard Edelstein, Srikanth Nagalla, Kathleen Delgrosso, Adam Ertel, Joan Kupper, Yi Jing, Eric R. Londin, Phillipe Loher, Huang-Wen Chen, Paolo Fortina, and Isidore Rigoutsos

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Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c., Leonard Edelstein, Lukas M Simon, Raúl Teruel Montoya, Michael Holinstat, Edward S Chen, Angela Bergeron, Xianguo Kong, Srikanth Nagalla, Narla Mohandas, David E Cohen, Jing-fei Dong, Chad Shaw, and Paul Bray

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Erosive arthritis and hepatic granuloma formation induced by peptidoglycan polysaccharide in rats is aggravated by prasugrel treatment., Analia E Garcia, Mario C Rico, Elisabetta Liverani, Raul A DeLa Cadena, Paul F. Bray, and Satya P Kunapuli

Submissions from 2012

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Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management., Samir K Ballas, Muge R Kesen, Morton F Goldberg, Gerard A Lutty, Carlton Dampier, Ifeyinwa Osunkwo, Winfred C Wang, Carolyn Hoppe, Ward Hagar, Deepika S Darbari, and Punam Malik

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Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1., Moritz Stolla, Jaroslav Pelisek, Marie-Luise von Brühl, Andreas Schäfer, Verena Barocke, Peter Heider, Michael Lorenz, Anca Tirniceriu, Alexander Steinhart, Johann Bauersachs, Paul F Bray, Steffen Massberg, and Christian Schulz

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Newer agents in antiplatelet therapy: a review., Jennifer Yeung and Michael Holinstat

Submissions from 2011

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Transfection of human platelets with short interfering RNA., Wei Hong, Altaf A Kondkar, Srikanth Nagalla, Wolfgang Bergmeier, Ying Jin, Jay Herman, and Paul Bray

Submissions from 2009

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Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD)., Vijay Nambi, Kay T Kimball, Paul Bray, Angela L Bergeron, Shawna L Johnson, Joel D Morrisett, Changyi Chen, Peter H Lin, Alan B Lumsden, Christie M Ballantyne, and Jing-Fei Dong

Submissions from 2008

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Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary events., Paul Bray, Joseph C Larson, Andrea Z Lacroix, Joann Manson, Marian C Limacher, Jacques E Rossouw, Norman L Lasser, William E Lawson, Marcia L Stefanick, Robert D Langer, and Karen L Margolis

Submissions from 2007

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Platelet hyperreactivity: predictive and intrinsic properties., Paul F. Bray

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Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays., Rani E George, Edward F Attiyeh, Shuli Li, Lisa A Moreau, Donna Neuberg, Cheng Li, Edward A Fox, Matthew Meyerson, Lisa Diller, Paolo Fortina, A Thomas Look, and John M Maris

Submissions from 2001

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Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway., Douglas Woods, Holly Cherwinski, Eleni Venetsanakos, Arun Bhat, Stephan Gysin, Martine Humbert, Paul F. Bray, Vicki L. Saylor, and Martin McMahon

Submissions from 2000

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The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions., K Vinod Vijayan, Pascal J. Goldschmidt-Clermont, Christine Roos, and Paul F. Bray

Submissions from 1999

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Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets., Ravinder Pabla, Andrew S. Weyrich, Dan A. Dixon, Paul F. Bray, Thomas M. McIntyre, Stephen M. Prescott, and Guy A. Zimmerman

Submissions from 1998

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Clinical problem-solving. Through thick and thin., David R. Yu, Redonda Miller, and Paul F. Bray

Submissions from 1996

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Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection., Ying Jin, Harry C. Dietz, Robert A. Montgomery, William R. Bell, Iain McIntosh, Barry Coller, and Paul F. Bray

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A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis., Ethan J. Weiss, Paul F. Bray, Matthew Tayback, Steven P. Schulman, Thomas S. Kickler, Lewis C. Becker, James L. Weiss, Gary Gerstenblith, and Pascal J. Goldschmidt-Clermont

Submissions from 1992

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Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein., Patrick F. Bray, J Luka, Paul F. Bray, K W. Culp, and J P. Schlight

Submissions from 1988

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Physical linkage of the genes for platelet membrane glycoproteins IIb and IIIa., Paul F. Bray, Greg Barsh, Jean-Philippe Rosa, Xue Ya Luo, Ellen Magenis, and Marc A. Shuman

Submissions from 1987

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Platelet Glycoprotein lib: Chromosomal Localization and Tissue Expression, Paul F. Bray, Jean-Philippe Rosa, Geoffrey I. Johnston, Donny T. Shiu, Richard G. Cook, Chris Lau, Yuet Wai Kan, Rodger P. McEver, and Marc A. Shuman

Submissions from 1986

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Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa., Paul F. Bray, Jean-Philippe Rosa, Vishwanath R. Lingappa, Yuet W. Kan, Rodger P. McEver, and Marc A. Shuman