Title

Urokinase Plasminogen Activator Expression is Regulated by p53 Harboring the Lung Cancer-Specific Mutation V157F

Authors

Julie Barta, MD, Thomas Jefferson UniversityFollow
Kristen Pauley, Thomas Jefferson UniversityFollow
Steven B. McMahon, PhD, Thomas Jefferson UniversityFollow

Files

Description

OBJECTIVES

• To define the mutant p53-regulated transcriptome of lung cancer cells with alterations at V157 and R158 in the p53 tumor suppressor.
• To determine the biological effects of lung-enriched p53 mutations in lung cancer cells.

Publication Date

1-9-2017

Keywords

poster, poster presentation, lung cancer, p53, tumor suppressor gene

Disciplines

Medical Biochemistry | Medical Molecular Biology | Medicine and Health Sciences | Pulmonology

Comments

Presented at the American Association of Cancer Research-International Association for the Study of Lung Cancer Fifth Annual AACR-IASLC Joint Conference

Recommended Citation

Barta, MD, Julie; Pauley, Kristen; and McMahon, PhD, Steven B., "Urokinase Plasminogen Activator Expression is Regulated by p53 Harboring the Lung Cancer-Specific Mutation V157F" (2017). Department of Biochemistry and Molecular Biology Posters. 1.
https://jdc.jefferson.edu/bmpposters/1