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- 2011 ACCF/AHA Guidelines for CABG: Uncertain about the safety of the preoperative administration of ACE inhibitors or ARBs in patients on chronic therapy and the safety of initiating ACE inhibitors or ARBs before hospital discharge
- 2014 ESC Guidelines: ACE inhibitors might be stopped 1 to 2 days before CABG to avoid the potential deleterious consequences of perioperative hypotension
- Guidelines state that ACE inhibitors or ARBs should be initiated postoperatively in CABG patients who were not receiving them preoperatively if they have an LVEF ≤40%, hypertension, diabetes, or CKD (Level of Evidence: A)
- There is still a lack of large clinical studies on the effects of perioperative use of RASi and long-term outcomes in cardiac surgery
cardiac surgery, ACE inhibitor, ARB, mortality, perioperative, renin-angiotensin system inhibitor
Anesthesiology | Cardiology | Medicine and Health Sciences | Surgery
Ding, Qian; Berguson, Mark; Zhang, Zugui; Liu, Hong; Nie, Huang; Goldhammer, Jordan E.; Morris, Rohinton J.; and Sun, Jianzhong, "Does Perioperative Use of Renin-Angiotensin System Inhibitors Improve Patient Outcomes in Cardiac Surgery?" (2019). Department of Anesthesiology Posters. 6.