Title

Transient increased exudation after photodynamic therapy of intraocular tumors.

Document Type

Article

Publication Date

1-1-2013

Comments

This article has been peer reviewed. It was published in: Middle East African journal of ophthalmology.

Volume 20, Issue 1, Jan-Mar 2013, Pages: 83-6.

The published version is available at DOI: 10.4103/0974-9233.106400. Copyright © Medknow

Abstract

To report transient increased exudation after photodynamic therapy (PDT) of three different intraocular tumors (retinal hemangioblastoma, retinal astrocytoma, amelanotic choroidal melanoma). PDT with verteporfin (6 mg/m(2) body surface area) was delivered at a dose of 50 J/cm(2) and intensity of 600 mW/cm(2) over 83 s. All patients experienced decreased vision within a few days following PDT. Optical coherence tomography showed development of subfoveal fluid in all cases and noncystoid intraretinal edema in the eye with juxtapapillary retinal hemangioblastoma. There was complete absorption of retinal/subretinal fluid with improvement of visual acuity to 20/20 in all cases between 3 weeks to 4 months after PDT.