The classic blue sclera of a patient with type 1 osteogenesis imperfecta. Due to a defect in type 1 collagen, the overlying sclera is abnormally thin, resulting in increased visibility of the underlying choroidal veins and the blue color of the eyes. This patient also had a history of more than forty bone fractures throughout his life.
Murphy, MD, Matthew A.
"Clinical Images: Physical Diagnosis: When Blue is a Clue,"
The Medicine Forum: Vol. 18
, Article 4.
Available at: http://jdc.jefferson.edu/tmf/vol18/iss1/4