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Theses/Dissertations from 1995

Cloning and characterization of murine All1 gene, Qing Ma

Cloning and characterization of the human A-myb gene, Xiaoping Ma

The immunological effects of intravesical BCG immunotherapy in a murine model of transitional cell carcinoma of the bladder, Kathleen Michelle McAveney

Structure and function of the versican gene, Michael F. Naso

The molecular pathogenesis of demyelination and CNS tumors induced by the neurotropic papovavirus, JCV, Ganesh V. Raj

The molecular and genetic characterization of the DAT1 gene product of Saccharomyces cerevisiae, Brian J. Reardon

Zinc finger proteins: a study of linker region importance, DNA, and RNA binding characteristics, Robert F. Ryan

IGF-I receptor signaling in mammalian cell growth and transformation, Jennifer L. Swantek

Phosphorylation-mediated regulation of crossbridge interaction in vascular smooth muscle, Laura Trinkle-Mulcahy

Cloning and characterization of the murine COL11A2 gene, its cDNA, and its functional analysis in transgenic mice, Philipp Vandenberg

Structural analysis of biopolymers using nuclear magnetic resonance and molecular modeling, James M. Varnum

Protective immunity to larval Onchocerca Volvulus in a mouse model, Wiboonchai Yutanawiboonchai

Heterologous expression of collagen genes toward a structural and functional analysis of the domains of procollagen, Khaja Zafarullah

Theses/Dissertations from 1994

Molecular analysis of gastrointestinal smooth muscle development in vitro, Jacqueline Welde Brittingham

Neutrophil functional and kinetic changes in a sheep model of endotoxemia, Lisa A. Carey

Mutations in the lysosomal b-galactosidase gene that cause the adult form of GM1 gangliosidosis, Sulagna Chakraborty

Effects of acetylsalicylic acid on fibrin clot cross-linking, lysis, and structure: in vivo and in vitro studies, Cynthia Cheng

Regulation of TGF-gbs gene expression in glial cells: implications for HIV-1-induced CNS dysfunction in AIDS, Crystina Cupp

Role of P-selectin and nitric oxide in leukocyte-endothelial interaction in the rat mesenteric microcirculation, Kelly L. Davenpeck

Identification of a pugative IGF-1 receptor signaling molecule, Guillaume Dumenil

Identification of a complex tandem repeat family in the human genome and characterization of one family member, a novel gene expressed in hemato-poietic lineages, Teresa Fernandes-Alnemri

Apoptosis in early mouse embryos as a determinant of abnormal development, Xiang Gao

The development of a recombinant system for the production of normal and substituted prod1(1) collagen: HT 180 cells that have been stably transfected with colia1 secrete homotrimeric collagen that is post-translationally modified and thermostable, Amy Elizabeth Geddis

Molecular genetics of human acute leukemia with chromosome translocation t(4;11) (q21;q23), Yansong Gu

Interaction of glucocorticoid receptor and protein kinase c-mediated signal transduction pathways, Tin-Chen Hsu

Isolation and characterization of suppressors of camptothecin toxicity in Saccharomyces cerevisiae, Eunkyung Ann Kauh

The molecular basis for camptothecin resistance in DNA topoisomerase I mutants, Anne M. Knab

Structural and functional characterization of B-adrenergic receptor Kinase, Guanghui Kong

Cloning, expression and characterization of a novel G Protein-coupled receptor kinase GRK5, Priya Kunapuli

Extracellular matrix proteins as stimulators of tissue-type plasminogen activator activity, Peter S. Liao

Cellular genes modulated by P53 protein, David Hua Lin

Analysis of patients displaying clinical findings associated with trisomy 18, Reema Mewar

The purification and characterization of a double-stranded DNA binding protein (uBP1) and a single-stranded DNA binding protein (uSSB1) from Ustilago maydis, Ronnie Myers

Characterization and developmental analysis of the cerebellum of the meander tail mutant mouse, Julie Anne Napieralski

The embryonic development and organization of the olivocerebellar and nucleo-olivary projection systems in the mouse, Michele A. Paradies

The role of mitochondrial dysfunction in hypoxic cell killing, John G. Pastorino

Metachromatic leukodystrophy among the Navajo Indians: a study of the arylsulfatase A gene mutations present in this population, Nuria Maria Pastor-Soler

Clathrin interactions with HSC70 and valosin-containing protein, Irene Tidikis Pleasure

Effects of ethanol on excitation-contraction coupling in single cardiomyocytes, Dennis John Rozanski

Phorbol esters suppress ornithine decarboxylase activity and alter odc subcellular localization concomitant with disruption of actin cytoskeleton in human epidermal cells, Kimberly Klimek Ruhl

Analysis of the role of a paired box gene in the development of the vertebral column, Carol Ann Smith

Study of the regulation of human CDC2 gene, Shau-Ching Wen

Theses/Dissertations from 1993

Characterization of an adenosine signalling mechanism in the early postimplantation mouse uterus, Michael Rex Blackburn

Cerebral microvascular endothelium and susceptibility to experimental allergic encephalomyelitis, Linda M. Dallasta

Transforming growth factor-B modulation of extracellular matrix metabolism by mesenchymal cells of the developing murine secondary palate, Marina D'Angelo

Characterization of protein and membrane trafficking pathways in malaria infected erythrocytes, Jill Ann Gormley

Nuclear proteins regulate transcription of the myelin basic protein gene during brain development, Susan Haas

Growth and metastasis of human melanoma in SCID mice: the effect of human natural killer cells on tumor growth in vivo, Laurie Lynn Hill

Mechanisms of immune-mediated killing of larval onchocerca volvulus in a mouse model, Anna Marie Lange

The role of the CDR3-like region of CD4 in T Cell activation, James M. McDonnell

N-cadherin-mediated cell adhesion during chondrogenesis in the chick embryonic limb bud, Steven Alan Oberlender

Purification and characterization of the endogenous proteolytically-derived turnover product of N-cadherin in the embryonic chick neural retina, Nancy Elaine Paradies

Mechanisms responsible for increased collagen gene expression in tight-skin (tsk) mice myocardial fibroblasts, Neena Philips

Differentiation-defective murine embryonal carcinoma cells: characterization of retinoic acid induced gene expression and rescue of phenotype by DNA transfection, Ellen J. Purpus

Myocardial and endothelial protective effects of nitric oxide donors in feline myocardial ischemia and reperfusion, Martin R. Siegfried

Adhesion of bone cells to orthopaedic implant materials, Raj K. Sinha

Myosin bound nucleotide in permeabilized smooth muscle: kinetics of turnover and regulation by light chain phosphorylation, Tapan B. Vyas

Regulation of cellular differentiation in the developing chick embryonic calvarium, Mayme Wong

Theses/Dissertations from 1992

Studies of the polyphosphate binding sites of clathrin assembly protein AP-2, Quan Chen

I. The incidence and physical characterization of Marek's disease herpesvirus in avian leukosis virus induced tumors: and II. The construction of a recombinant vaccinia virus expressing Marek's disease virus nia virus expressing Marek's disease virglycoprotein A, Ellen Frances Fynan

Characterization and modulation of the transforming growth factors B in the murine embryonic palate, Amy Lynne Gehris

An in vivo characterization of the stress response in dopaminergic systems: modulation by the anxiolytics ethanol and diazepam, Allison Adams Hegarty

A study of the regulation of human c-myb gene expression, Nicholas C. Nicolaides

The induction of monocytopoiesis in HL-60 promyelocytic leukemia cells is inhibited by hydroquinone, a toxic metabolite of benzene, Nancy L. Oliveira

Effects of bacterial endotoxin on arachidonic acid metabolism in rabbit microvascular endothelial cells, Paula M. Renzi

The antiproliferative effects of the human wild type P53 gene, Michele T. Shields

The effects of anti-IL2 receptor monoclonal antibodies on the development of experimental allergic encephalomyelitis, Ligang Shi

Tonic descending modulation of spinal neurons receiving input from renal afferent nerve fibers, Amelia Standish

Characterization of the structure and alternative splicing of the human a3 type VI collagen gene, David G. Stokes

Regulation of the JC virus lytic cycle, Hiroomi Tada

Regulation of HIV-1 gene expression in the central nervous system, J Paul Taylor

Renal afferent input to the ventrolateral medulla of the cat, Margaret A. Vizzard

Theses/Dissertations from 1991

Relationship between endocytosis of antigen receptors and activation of murine B lymphocytes

In vivo modulation of excitatory amino acid receptors: microdialysis studies on Kainate and N-methyl-d-aspartate-evoked striatal dopamine release and effects of antagonists, David Paul Carrozza

Eicosanoid synthesis by the murine fetal thymus, Kimberly J. Pendino-Shuler

A role for interleukin-1 in benzene-induced hematotoxicity: inhibition of the conversion of pre-IL-1[alpha] to mature cytokine in murine macrophages by hydroquinone and the prevention of benzene-induced hematotoxicity in mice by interleukin-1[alpha], John F. Renz

A direct demonstration of copolymerization of pNcollagen III with collagen I in vitro, Anne M. Romanic

The development of a novel method of proteinpeptide sequence analysis from the C-terminus (the dipeptidyl exopeptidase method) and its use to determine the sequence of a Ficus Glabrata tryptic peptide, Teresa Ann Smith

Time course and mechanism of endothelial dysfunction in the ischemic-reperfused feline myocardium, Philip S. Tsao

Theses/Dissertations from 1990

Purification and characterization of the Mutl gene product of escherichia coli, Steven M. Bende

Cardiovascular and catecholamine stress responses in rats: modification by anxiolytics or isoproterenol-induced myocardial infarction, Melanie Krieman Boerner

Effect of stimulation on hexose transport in the frog sartorius: kinetics and properties of the system, George Warren Booz

Analysis of cell adhesion and differentiation in the retinal pigment epithelium, Peiguo Chu

The effect of botulinum C toxin and tetanus toxin on cell secretory processes: related clostridial toxins with different modes of action, Robert Vincent Considine

The effect of glucose and acetyl-l-carnitine on energy metabolities, lipid peroxidation and glutathione during and following hypoxia in the rat hippocampal slice, Glenn D. Frazer

Salicylate-induced nephrotoxicity in the laboratory rat: effects of age, sex and strain, Peter A. Glascott

Sources and control of release of plasma catecholamines in the American eel, Anquilla rostrata (teleostei), Charles Briggs Hathaway

Transport of doxorubicin in calcium-resistant cardiac myocytes isolated from the adult rat heart, Vinod K. Khetarpal

Unusual immunomodulatory activities of the random polymer (Glu, Phe) in murine T cell systems, Donald Chua Liu

Formation, characteristics and biological effects of n-a cetylamoxapine: an in vivo and in vitro product of amoxapine with aspirin, Robert A. Middleberg

Measurement of free and conjugated amino compounds in mammalian CNS: a prototype approach resulting in the detection of several novel GABA- containing compounds, Joanne M. Miller

The effects of a-adrenergic receptor activation on the cytosolic calcium transient, contractility, and transmembrane signalling in cardiac cells, Brian O'Rourke

The effects of hypercholesterolemia on the vasculature and the severity of myocardial ischemia in the rabbit, John A. Osborne

Conductivity behavior of nonionic surfactants in the design of perfluorocarbon emulsions, Jean Marie Pasternacki

The effects of hyperglycemia on human endothelial cell cytoskeletal function, Kerri J. Pratt

Regulation of N-cadherin expression during chick neural retina development, Eileen Frances Roark

A role for macrophage prostaglandin H synthase in the bioactivation of the benzene metabolite, hydroquinone, to a reactive intermediate that binds to and damages DNA, Robert D. Shurina

Characterization of a single-base mutation in the proa1(III) collagen gene of one proband with a variant of Ehlers-Danlos Syndrome type IV, Mijin Zhao

Theses/Dissertations from 1989

In vitro effects of sera from stressed rats on growth parameters of normal and transformed rat cells, David B. Bower

Characterization of blood and bone marrow neutrophil function associated with acute lung injury, Franklin Cerasoli