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Theses/Dissertations from 1999

A 23 base pair sequence element and its role in JC virus gene transcription, Mahmut Safak

Effects of transforming growth factor Beta-1 and bone morphogenetic protein-2 on osteoblats [i.e. osteoblasts] at the bone-biomaterial interface, Asit K. Shah

Members of the Meis1 homeoprotein family are involved in binding the Laminin gbs1 enhancer, Scott Steelman

Fluid shear stress-induced reorganization of adherens junctions in human endothelial cells, Jon A. Ukropec

The role of tripeptidyl peptidase II in MHC class I-restricted antigen processing and the effect of epitope density on CD8+ T cell priming, Edward John Wherry

Theses/Dissertations from 1998

Identification of a novel interaction between the N-terminal domain of fibrin and VE-cadherin: its role in angiogenesis, Tami Lee Bach

Natural killer cell differentiation, Ian Moore Bennett

Two MHC class II-restricted epitopes are processed in distinct eendocytic compartments as a result of the acid-induced structural changes in a viral glycoprotein, Kimberly A. Chianese-Bullock

Molecular determinants of zinc finger RNA interaction and development of specific RNA binding proteins, Westley J. Friesen

Activation mechanisms of phospholipase D: an ethonol metabolizing enzyme, Ramon J. Garcia

Interaction between the human mismatch repair proteins: association with hereditary nonpolyposis colorectal cancer, Shawn Robert Guerrette

Expression of the heparan sulfate proteoglycan perlecan during murine embryogenesis and tumorigenesis, Melissa Handler

Placental 57 kDa Ca2+ binding protein: regulation of expression and function in trophoblast differentiation and calcium homeostasis, Marcia E. Hershberger

The effects of Rb2p130 on tumorigenesis, Candace M. Howard-Claudio

The mechanisms of inactivation in brain potassium channels: molecular gates and shutters, Henry Hungtao Jerng

Transcriptional regulation of the human a2 (I) collagen (COL1A2) gene by tumor necrosis factor-a and interferon-g, David Jonathan Kouba

Characterization of the PITALRECDK9 and PISSLRE CDC2-related kinases, Timothy K. MacLachlan

Characterization of the receptor protein tyrosine phosphatase gamma gene product, Jeannine Mendrola

Effects of peroxynitrite, a reactive oxygen species, in myocardial reperfusion injury, Tareck O. Nossuli

Characterization of the mu opioid receptor in C57BL6J and DBA2J mice: with emphasis on the effects of repeated exposure to morphine, Rebecca Lynne Petruzzi

Elucidation of the mechanism and pathways promoting intestinal smooth muscle cell differentiation, Christopher J. Phiel

Molecular models for studying CNS associated tumors and dysmyelination, Adrienne Rencic

Novel HIV-1 therapeutic agents based on virion targeted viral proteins, Dawn M. Serio

A comparative study of the modes of activation of protein kinase C, Frank J. Taddeo

The ins and outs of macromolecular transport in malaria-infected erythrocytes, Darin P. Trelka

Organization of B1 integrin and N-cadherin mediated adhesion complexes during lens cell differentiation, Robert W. Veneziale

Genetic analysis of a mitogen-activated protein kinase required for spore morphogenesis in Saccharomyces cerevisiae, Marisa Wagner

A model for p53 gene-teratogen interaction in early mouse embryos, Judith Afedua Wubah

Purification and identification of a growth factor that sustains the growth of fibroblasts null for the IGF-I receptor, Shi-qiong Xu

Theses/Dissertations from 1997

Analysis of ectopic A-myb expression using a transgenic mouse model, Susan E. Derocco

Mechanisms underlying receptor-effector coupling of guanylyl cyclase C, Sujata Deshmane

The role of the B-myb gene in differentiation, Andrew G. Engelhard

Characterization of the human B1-adrenergic receptor gene and its transcriptional regulation, Daniel S. Evanko

Molecular characterization of the hypervariable yellow (Ahvy) allele at the murine agouti locus and investigation of factors influencing phenotypic variablity, Alysia Argeson Finnegan

Clathrin lattice assembly and adaptor recruitment in receptor-mediated endocytosis, Oscar Baylin Goodman

Chondrogenic induction by bone morphogenetic protein-2: involvement of N-cadherin-associated functions, Andrew R. Haas

Investigations into mitogen-activated protein (MAP) kinase signal transduction pathways in Saccharomyces cerevisiae, J Perry Hall

Development of a murine model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) susceptibility for quantitative trait locus mapping, Michael Koblish

Inhibition of bone marrow and skin graft rejection by a synthetic CD4-CDR3 peptide analog in murine transplantation models, Ute Koch

The molecular and cellular chracterization of Nck, an SH2SH3 adaptor protein, in signal transduction, Deirdre C. Lawe

Molecular genetics of the 180-kDa bullous pemphigoid antigen (BPAG2COL17A1), a transmembrane protein of the basement membrane zone of the stratifying squamous epithelia, Maria Isabel Limardo

Pathways of lipopolysaccharide-induced prostaglandin E2 production in human microvascular endothelial cells, Kimberly Anne Lucas

Secretory phospholipase A2: a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia, Melina MacPhee-Pellini

Cloning and characterization of the DR-nm23 gene and its associated product, a novel member of the nm23 gene family, Robert V P Martinez

Characterization of the transcriptional regulatory functions of the transforming region of the adenovirus E1A oncoprotein, Nianli Sang

The molecular characterization of chromosome 18 abnomalities associated with specific phenotypes, Leslie Sell

Characterization and analysis of the murine cartilage oligomeric matrix protein (COMP) gene, Christopher W. Slavinsky

Characterization of Ustilago maydis topoisomerase I: purification, cloning, biochemical and kinetic analysis, Manimekalai M. Thiyagarajan

Molecular mechanisms of myelination: implications in JCV-induced pathogenesis, Anna Tretiakova

The human COL1A1COL2A1 chimeric gene in transgenic mice: analysis of the mRNA expression and the apparent inhibition of translation from the construct, Constance Miao-Leng Yuan

Theses/Dissertations from 1996

Guide to the Ph.D. degree and thesis manual

mob-1, a novel mediator of ARDS, Fizan Abdullah

The creation of a DNA cassette system for the assembly of constructs encoding novel recombinant type II procollagens and an analysis of the thermal stability of these proteins, William Vincent Arnold

Cellular pharmacology of oligonucleotide analogs, Soumitra Basu

Role of immunodominant T cell responses to minor histocompatibility antigens in a mouse model of graft-versus-host disease, Marc Adam Berger

MHC class I-restricted cryptic epitopes: their production and immunogenicity, Timothy N J Bullock

Structural and functional analysis of the two human tumor necrosis factor receptors, Paul Chih-Hsueh Chen

Structure-based designed CD8 peptide analogs inhibit both in vitro and in vivo CD8 T cell responses, Swati Choksi

Retinoid signaling and cell cycle regulation during murine palate development, Patrick R. Connelly

Chromatin associated proteins of Ustilago maydis, Seema Dutta

High-throughput DNA sequence analysis for the investigation of genetic diseases by the candidate gene approach, James J. Earley

The phenotypic mapping of the cat-like cry observed in the cri-du-chat-syndrome and molecular characterization of the proposed critical region, Meryl Hope Gersh

Hydroquinone, a major bone marrow metabolite of benzene, induces granulopoiesis in a mouse model: possible role in benzene-induced acute myelogenous leukemia, Betsy Ann Hazel

Partial analysis of sequences expressed by human osteoblasts in vitro using differential display-PCR (DD-PCR), Jason E. Hill

Structure function analysis of BCL2gas and characterization of BMP7 null mice, Nilamani Jena

Structural and functional analysis of domains within the E2F1 transcription factor, Kelly Lynn Jordan

Differential regulation of collagenase and type I collagen gene expression by basic fibroblast growth factor in human smooth muscle cells, Susan H. Kennedy

Biochemical and functional analysis of N-cadherin phosphorylation in embryonic chick tissues, Mimi Meihui Lee

A CD4-CDR3 peptide analog inhibits both primary and secondary CD4 T cell responses in experimental allergic encephalomyelitis, Joseph C. Marini

Mutant DNA topoisomerase I-induced lethality in Saccharomyces cerevisiae, Maureen D. Megonigal

The role of transforming growth factor-beta 1 and thyroid hormone in the regulation of endochondral ossification, Maria Alice Mello

Identification and characterization of Meis1, a common site of viral integration involved in murine myeloid leukemia, John J. Moskow

The role of RAD1 in repeat-mediated double strand break repair of Variable Number Tandem Repeats (VNTRs) in Saccharomyces cerevisiae, Johanna C. Mylet

Adenine nucleotide regulation of receptor guanylyl cyclases: application to interrupt Escherichia coli heat-stable interotoxin-dependent signalling mediating secretory diarrhea, Scott James Parkinson

Ornithine decarboxylase and the cytoskeleton in normal human epidermal keratinocytes: regulation of activity by subcellular localization and cytoskeletal organization, Mary Martha Pomidor

Molecular genetic analysis of N-cadherin structure and function, Matthew James Rock

Protective immunity to larval Strongyloides stercoralis in a mouse model, Harris L. Rotman

Transcriptional regulation of epidermal-specific cell adhesion molecules, Stephanie A. Silos

Molecular and cytogenic analysis of the 18q- syndrome, Gordon R. Strathdee

Effect of TGF-B superfamily members on limb mesenchymal chondrogenesis in vitro: modulation of N-cadherin and catenin expression and association, William Andrew Tyndall

Molecular characterization of the canine model for globoid cell leukodystrophy (Krabbe disease) and study of the effects of human polymorphisms on the activity of murine galactocerebrosidase, Teresa Victoria

A molecular and genetic analysis of variable number tandem repeat (VNTR) recombination in Saccharomyces cerevisiae, Eric J. Weaver

Voltage-activated gating of sodium channels, Naibo Yang

Theses/Dissertations from 1995

Thesis manual: guidelines, admission of a student to candidacy for the degree of Doctor of Philosophy, and writing the thesis.

Antibody and complement mediated immunity to infective and autoinfective third stage larvae of Strongyloides stercoralis, Richard A. Brigandi

Molecular characterization of the t(2;5) translocation and of 13q14 deletions in hematopoietic malignancies, Florencia E S Bullrich

Molecular regulation and antiviral studies on DNA replication of human neurotropic JC virus, Chun-Fan Chang

Identification and characterization of cellular proteins regulating transcription of human neurotropic virus, JCV, Nancie Nien-Tsyr Chen

Chondrogenic activity of transforming growth factor-B1 and bone morphogenic protein-2 on multipotential mesenchymal cells, Andrew Evan Denker

NMRtransferred NOE studies of fibrinogen derived peptides and binding to platelet integrin IIbIIIa, Francis Chaochia Fan

Protein trafficking pathways in the malarial parasite, Plasmodium falciparum, Michael Alan Feldman

Mechanisms of vascular protection by nitric oxide donors in a rat model of carotid artery injury, Jin-ping Guo

Cloning and characterization of loci surrounding the familial renal cell carcinoma t(3;8) translocation breakpoint, Kumar Kastury

Molecular regulation of the human neurotropic virus JCV, Douglas A. Kerr

Homologous pairing of nucleosomal DNA mediated by transcription, Hidehito Kotani

In vivo gene therapy: using a recombinant vaccinia virus as a cytokine gene delivery system to localized murine tumors, Sharon Sunmi Lee

Regulation of intracellular inositol 1,4,5-triphosphate-sensitive Ca2+ release, Chi Lin

Cadmium effects on trophoblast calcium transport, Fang-Ju Lin

An E2F binding sequence regulates the activation of the IGF-I promoter by PDGF and EGF, Shu Li

Analysis of the role of the E2F1 transcription factor in the mammalian cell cycle, Thomas J. Logan