Reports to NTPR to date continue to reveal an increased incidence of birth defects in transplant recipients maintained on MPA products during gestation compared to those not maintained on these agents.
Structural birth defects consisting of microtia (ear deformity) and facial defects suggest a pattern of malformations.
Evaluation of the higher incidence of non-viable outcomes requires further study in this cohort.
Centers are encouraged to report all pregnancy exposures in transplant recipients to the NTPR.
Recommended CitationNguyen, To Dung K.; Carlin, Faith; Coscia, Lisa A.; Armenti, Dawn; and Armenti, Vincent T., "Pregnancy Outcomes with Exposure to the Mycophenolic Acid Products (MPA)" (2010). Department of Surgery Faculty Papers & Presentations. Paper 27.