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Submissions from 2013

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Bortezomib (PS-341) treatment decreases inflammation and partially rescues the expression of the dystrophin-glycoprotein complex in GRMD dogs., Karla P C Araujo, Gloria Bonuccelli, Caio N Duarte, Thais P Gaiad, Dayson F Moreira, David Feder, José E Belizario, Maria A Miglino, Michael P Lisanti, and Carlos E Ambrosio

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Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development., Christiane Danilo, Jorge L Gutierrez-Pajares, Maria Antonietta Mainieri, Isabelle Mercier, Michael P. Lisanti, and Philippe G. Frank

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Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide., Kevin Quann, Donna M Gonzales, Isabelle Mercier, Chenguang Wang, Federica Sotgia, Richard G Pestell, Michael P Lisanti, and Jean-François Jasmin

Submissions from 2012

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CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis., Claudia Capparelli, Barbara Chiavarina, Diana Whitaker-Menezes, Timothy G Pestell, Richard Pestell, James Hulit, Sebastiano Andò, Anthony Howell, Ubaldo E. Martinez-Outshoorn, Federica Sotgia, and Michael P. Lisanti

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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production., Claudia Capparelli; Carmela Guido; Diana Whitaker-Menezes, PhD; Gloria Bonuccelli; Renee Balliet; Timothy G Pestell; Allison F Goldberg; Richard Pestell; Anthony Howell; Sharon Sneddon; Ruth Birbe; Aristotelis Tsirigos; Ubaldo E. Martinez-Outshoorn; Federica Sotgia; and Michael P. Lisanti

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CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth., Claudia Capparelli, Diana Whitaker-Menezes, Carmela Guido, Renee Balliet, Timothy G Pestell, Anthony Howell, Sharon Sneddon, Richard Pestell, Ubaldo E. Martinez-Outshoorn, Michael P. Lisanti, and Federica Sotgia

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Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth., Valentina Carito, Gloria Bonuccelli, Ubaldo E Martinez-Outschoorn, Diana Whitaker-Menezes, Maria Cristina Caroleo, Erika Cione, Anthony Howell, Richard G Pestell, Michael P. Lisanti, and Federica Sotgia

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Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth., Carmela Guido, Diana Whitaker-Menezes, Zhao Lin, Richard G Pestell, Anthony Howell, Teresa A Zimmers, Mathew C Casimiro, Saveria Aquila, Sebastiano Ando', Ubaldo E Martinez-Outschoorn, Federica Sotgia, and Michael P Lisanti

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Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells., Ahmed F Salem, Diana Whitaker-Menezes, Zhao Lin, Ubaldo E. Martinez-Outshoorn, Herbert B Tanowitz, Mazhar Salim Al-Zoubi, Anthony Howell, Richard Pestell, Federica Sotgia, and Michael P. Lisanti

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Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation., Emily J Tsai, Yuchuan Liu, Norimichi Koitabashi, Djahida Bedja, Thomas Danner, Jean-Francois Jasmin, Michael P Lisanti, Andreas Friebe, Eiki Takimoto, and David A Kass

Submissions from 2011

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Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?, Federica Sotgia, Ubaldo E Martinez-Outschoorn, and Michael P Lisanti

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Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment., Federica Sotgia, Ubaldo E Martinez-Outschoorn, Stephanos Pavlides, Anthony Howell, Richard G. Pestell, and Michael P Lisanti

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Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?, Federica Sotgia, Ubaldo E. Martinez-Outshoorn, and Michael P. Lisanti

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Complex alternative splicing of the smarca2 gene suggests the importance of smarca2-B variants., Min Yang, Yuan Sun, Ling Ma, Chenguang Wang, Jian-Min Wu, Anding Bi, and D Joshua Liao

Submissions from 2010

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A biological global positioning system: considerations for tracking stem cell behaviors in the whole body., Shengwen Calvin Li, Lisa May Ling Tachiki, Jane Luo, Brent A Dethlefs, Zhongping Chen, and William G Loudon

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Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"., Stephanos Pavlides, Aristotelis Tsirigos, Iset Vera, Neal Flomenberg, Philippe G. Frank, Mathew C Casimiro, Chenguang Wang, Richard Pestell, Ubaldo E. Martinez-Outshoorn, Anthony Howell, Federica Sotgia, and Michael P. Lisanti

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CAV1 inhibits metastatic potential in melanomas through suppression of the Integrin/Src/FAK signaling pathway., Casey Trimmer, Diana Whitaker-Menezes, Gloria Bonuccelli, Janet N Milliman, Kristin M Daumer, Andrew E Aplin, Richard G Pestell, Federica Sotgia, Michael P Lisanti, and Franco Capozza

Submissions from 2009

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Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders., Isabelle Mercier, Jean-Francois Jasmin, Stephanos Pavlides, Carlo Minetti, Neal Flomenberg, Richard G Pestell, Philippe G Frank, Federica Sotgia, and Michael P Lisanti