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Manuscripts from 2014

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ASA Section on Teaching of Statistics in the Health Sciences: 25 Years Later, Constantine Daskalakis, ScD

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Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects., Walter K. Kraft, Peter S. Chang, Marlou L P S van Iersel, Hetty Waskin, Gopal Krishna, and Wendy M Kersemaekers

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Ethanol Pharmacokinetics in Neonates and Infants, Elizabeth Marek, PharmD. and Walter K. Kraft, MD

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Impact of Preadmission Beta-blocker Use on Cardiac Abnormalities and In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage, Toshimasa Okabe, MD; Anushya Jeyabalan, MD; Benjamin E. Leiby, PhD; Fred Rincon, MD; and Walter K. Kraft, MD

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Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C., Matthew Witek, Erik S Blomain, Michael Sullivan Magee, Bo Xiang, Scott A Waldman, and Adam E. Snook

Manuscripts from 2013

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Mechanisms of Weight Regain following Weight Loss, Erik Scott Blomain, Dara Anne Dirhan, Michael Anthony Valentino, Gilbert Won Kim, and Scott A Waldman

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The Impact of Community Use of Novel Oral Anticoagulants on an Academic Medical Center, Luis Eraso, MD; Taki Galanis, MD; Kristina Kipp, Pharm.D.; Walter K. Kraft, MD; Michael Palladino, Pharm.D., CACP; Alejandro Perez, MD; Kimberle Ferebee-Spruill, CRNP; Geno Merli, MD; Brian G. Swift, Pharm.D., MBA; Lynda Thomson; and Brittany Vining

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Molecular staging of node negative patients with colorectal cancer., Terry Hyslop and Scott A Waldman

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Increased levels of plasma soluble Sema4D in patients with heart failure., Qiongyu Lu, Ningzheng Dong, Qi Wang, Wenxiu Yi, Yuxin Wang, Shengjie Zhang, Haibo Gu, Xin Zhao, Xiaorong Tang, Boquan Jin, Qingyu Wu, Lawrence F Brass, and Li Zhu

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Management of intracranial bleeding associated with dabigatran use in a neuroscience hospital, Alejandro Perez, MD; Lynda Thomson; and Geno J. Merli, MD

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Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis., Giovanni M Pitari

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Poor Positive Predictive Value of McConnell’s Sign on Transthoracic Echocardiography for the Diagnosis of Acute Pulmonary Embolism, Urvashi Vaid, MD, MS; Esme Singer, MD; Gregary D. Marhefka, MD; Walter K. Kraft, MD; and Michael Baram, MD, FCCM

Manuscripts from 2012

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Dysregulation of miR-31 and miR-21 Induced by Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, and Louise Fong

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Effect of Concomitant Medications Affecting Gastric pH and Motility on Posaconazole Tablet Pharmacokinetics, Walter K. Kraft, P. Chang, MLPS Van Iersel, H. Waskin, G. Krishna, and W. Kersemaekers

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Pharmacologic management of the opioid neonatal abstinence syndrome., Walter K. Kraft and John N van den Anker

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Healthy Volunteer Registries and Ethical Research Principles, Erine A. Kupetsky-Rincon and Walter K. Kraft

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GUCY2C Opposes Systemic Genotoxic Tumorigenesis by Regulating AKT-Dependent Intestinal Barrier Integrity, Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz, and Scott Arthur Waldman

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Molecular staging individualizing cancer management, Alex Mejia, Stephanie Schulz, Terry Hyslop, David S. Weinberg, and Scott A. Waldman

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MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics and Pharmacodynamic Electrophysiology in Experimental Animal Models and in Humans., Behzad B. Pavri, Howard E Greenberg, Walter K. Kraft, Nicole Lazarus, Joseph J Lynch, Joseph J Salata, Mark T Bilodeau, Christopher P Regan, Gary Stump, Li Fan, Anish Mehta, John A Wagner, David E Gutstein, and Daniel Bloomfield

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Advancing pharmacometrics and systems pharmacology., Scott A. Waldman and Andre Terzic

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The value proposition of molecular medicine., Scott A. Waldman and Andre Terzic

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Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer., David S Zuzga, Joshua Pelta-Heller, Peng Li, Alessandro Bombonati, Scott A Waldman, and Giovanni Mario Pitari

Manuscripts from 2011

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Analysis of the proteome of human airway epithelial secretions., Mehboob Ali, Erik P Lillehoj, Yongsung Park, Yoshiyuki Kyo, and K Chul Kim

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Formulation of buprenorphine for sublingual use in neonates., Ellena A Anagnostis, Rania E Sadaka, Linda A Sailor, David E Moody, Kevin C Dysart, and Walter k. Kraft

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The effects of laropiprant, a selective prostaglandin D₂ receptor 1 antagonist, on the antiplatelet activity of clopidogrel or aspirin., Aimee Dallob, Wen-Lin Luo, Julie Mabalot Luk, Lisa Ratcliffe, Amy O Johnson-Levonas, Jules I Schwartz, Victor Dishy, Walter K. Kraft, Jan N De Hoon, Anne Van Hecken, Inge De Lepeleire, Waldemar Radziszewski, John A Wagner, and Eseng Lai

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The incidence of deep vein thrombosis detected by routine surveillance ultrasound in neurosurgery patients receiving dual modality prophylaxis., Patricia C Henwood, Thomas M Kennedy, Lynda Thomson, Taki Galanis, George L Tzanis, Geno J Merli, and Walter K. Kraft

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Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome., Walter K Kraft, Kevin Dysart, Jay S Greenspan, Eric Gibson, Karol Kaltenbach, and Michelle E Ehrlich

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Chronic diseases: the emerging pandemic., Andre Terzic and Scott A. Waldman

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A uroguanylin-GUCY2C endocrine axis regulates feeding in mice., Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, and Scott A Waldman

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Bionic Technologies Transforming the Science of Healthcare Delivery, Scott A. Waldman , M.D., Ph.D and Andre Terzic , M.D., Ph.D

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Clinical pharmacology as a foundation for translational science., Scott A. Waldman, R J. Hohl, G L. Kearns, S J. Swan, and A Terzic

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Clinical Translational Science 2020: Disruptive Innovation Redefines the Discovery-Application Enterprise, Scott A. Waldman and Andre Terzic

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Year in Review, Scott A. Waldman and Andre Terzic

Manuscripts from 2010

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Selection of optimal reference genes for normalization in quantitative RT-PCR., Inna Chervoneva, Yanyan Li, Stephanie Schulz, Sean Croker, Chantell Wilson, Scott A Waldman, and Terry Hyslop

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Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics., Jieru E Lin, Michael A. Valentino, Glen Marszalowicz, Michael S Magee, Peng Li, Adam E. Snook, Brian Arthur Stoecker, Chang Chang, and Scott A Waldman

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Survival associated pathway identification with group Lp penalized global AUC maximization., Zhenqiu Liu, Laurence S Magder, Terry Hyslop, and Li Mao

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Identification of thioaptamer ligand against E-selectin: potential application for inflamed vasculature targeting., Aman P Mann, Anoma Somasunderam, René Nieves-Alicea, Xin Li, Austin Hu, Anil K Sood, Mauro Ferrari, David G Gorenstein, and Takemi Tanaka

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Molecular staging estimates occult tumor burden in colorectal cancer, Alex Mejia, Stephanie Schulz, Terry Hyslop, David S. Weinberg, and Scott A. Waldman

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Sizing up pharmacotherapy for obesity., Michael A. Valentino, Andre Terzic, and Scott A. Waldman

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Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas., Brody Winn, Rosemarie Tavares, Andres Matoso, Lelia Noble, Jacqueline Fanion, Scott A Waldman, and Murray B Resnick

Manuscripts from 2009

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Targeting the cGMP Pathway to Treat Colorectal Cancer, Giovanni Mario Pitari

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Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease., Adam E. Snook, Peng Li, Benjamin J Stafford, Elizabeth J Faul, Lan Huang, Ruth C Birbe, Alessandro Bombonati, Stephanie Schulz, Matthias J. Schnell, Laurence C. Eisenlohr, and Scott A. Waldman

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A glycosylated recombinant human granulocyte colony stimulating factor produced in a novel protein production system (AVI-014) in healthy subjects: a first-in human, single dose, controlled study., Roslyn Varki, Ed Pequignot, Mark C Leavitt, Andres Ferber, and Walter K Kraft

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Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer., Scott A Waldman, Terry Hyslop, Stephanie Schulz, Alan Barkun, Karl Nielsen, Janis Haaf, Christine Bonaccorso, Yanyan Li, and David S Weinberg

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A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer., Scott A Waldman and Andre Terzic

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Prediction of Sublingual Bioavailability of Buprenorphine in Newborns with Neonatal Abstinence Syndrome—a case study on physiological and developmental changes using NONMEM and SIMCYP, Di Wu, Walter K. Kraft, Michelle E. Ehrlick, and Jeffrey S. Barnett

Manuscripts from 2008

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Tumor Epithelial Cell Matrix Metalloproteinase 9 (MMP-9) is a Prognostic Marker in Colorectal Cancer, DS Zuzga, AV Gibbons, P Li, WJ Lubbe, I Chervoneva, and Giovanni Mario Pitari

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Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells, Giovanni Mario Pitari, Jieru E. Lin, Fawad J. Shah, Wilhelm J. Lubbe, David Zuzga, Peng Li, Stephanie Schulz, and Scott A Waldman

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Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis., David S Zuzga, Ahmara Vivian Gibbons, Peng Li, Wilhelm Johannes Lubbe, Inna Chervoneva, and Giovanni Mario Pitari

Manuscripts from 2007

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The pharmacokinetics of taurolidine metabolites in healthy volunteers., Li Gong, Howard E Greenberg, James L Perhach, Scott A Waldman, and Walter K. Kraft

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Transgenic avian-derived recombinant human interferon-alpha2b (AVI-005) in healthy subjects: an open-label, single-dose, controlled study., T B Patel, E Pequignot, S H Parker, M C Leavitt, H E Greenberg, and Walter K. Kraft

Manuscripts from 2004

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Nuovi Approcci Terapeutici contro il Cancro del Colon, Giovanni Mario Pitari

Manuscripts from 2001

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Guanylyl Cyclase C (GC-C) Inhibits Human Colon Carcinoma Cell Growth, Giovanni Mario Pitari

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Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells., Giovanni Mario Pitari, M D Di Guglielmo, J Park, S Schulz, and Scott A Waldman

Manuscripts from 1979

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A scale for assessing the severity of diseases and adverse drug reactions: Application to drug benefit and risk, Ronald J. Tallarida, Rodney B. Murray, and Carl Eiben