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Manuscripts from 2008

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A construct with fluorescent indicators for conditional expression of miRNA., Linghua Qiu, Hongyan Wang, Xugang Xia, Hongxia Zhou, and Zuoshang Xu

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The Value of Intraoperative Examination of Axillary Sentinel Nodes in Carcinoma of the Breast., Gordon F. Schwartz, Lauren S. Krill, Juan P. Palazzo, and Abhijit Dasgupta

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Fibulin-2 is dispensable for mouse development and elastic fiber formation, Francois-Xavier Sicot, Takeshi Tsuda, Dessislava Markova, John Klement, Machiko Arita, Rui-Zhu Zhang, Te-Cheng Pan, Robert P. Mecham, David E. Birk, and Mon-Li Chu

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Multi-scale modeling of angiotensin II induced neuronal regulatory mechanisms in the brain, Rajanikanth Vadigepalli

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Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15., Nicholas J Wang, Alexander S Parokonny, Karen N Thatcher, Jennette Driscoll, Barbara M Malone, Naghmeh Dorrani, Marian Sigman, Janine M LaSalle, and N Carolyn Schanen

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Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts., Hua Zhang, Sudipto Das, Quan-Zhen Li, Ioannis Dragatsis, Joyce Repa, Scott Zeitlin, György Hajnóczky, and Ilya Bezprozvanny

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Proteomic profiling of endorepellin angiostatic activity on human endothelial cells., Jason J Zoeller and Renato V Iozzo

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A central function for perlecan in skeletal muscle and cardiovascular development, Jason J. Zoeller, Angela McQuillan, John Whitelock, Shiu-Ying Ho, and Renato V. Iozzo

Manuscripts from 2007

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Renal cell carcinoma metastatic to the duodenum: Treatment by classic pancreaticoduodenectomy and review of the literature, Robert Adamo, Patrick J. Greaney Jr., Agnieszka Witkiewicz, Eugene P. Kennedy, and Charles J. Yeo

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Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses., Marc R Birtwistle; Mariko Hatakeyama; Noriko Yumoto; Babatunde A Ogunnaike; Jan B. Hoek; and Boris N. Kholodenko PhD, DSci

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A dipeptidyl aminopeptidase-like protein remodels gating charge dynamics in Kv4.2 channels, Kevin Dougherty and Manuel Covarrubias

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Department of Pathology, Thomas Jefferson University, Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors., Jason I Herschkowitz, Karl Simin, Victor J Weigman, Igor Mikaelian, Jerry Usary, Zhiyuan Hu, Karen E Rasmussen, Laundette P Jones, Shahin Assefnia, Subhashini Chandrasekharan, Michael G Backlund, Yuzhi Yin, Andrey I Khramtsov, Roy Bastein, John Quackenbush, Robert I Glazer, Powel H Brown, Jeffrey E Green, Levy Kopelovich, Priscilla A Furth, Juan P Palazzo, Olufunmilayo I Olopade, Philip S Bernard, Gary A Churchill, Terry Van Dyke, and Charles M Perou

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Untangling the signalling wires, Boris N. Kholodenko PhD, DSci

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The enigma of struma ovarii, Lawrence M. Roth and Aleksander Talerman

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Bladder inflammatory transcriptome in response to tachykinins: Neurokinin 1 receptor-dependent genes and transcription regulatory elements, Ricardo Saban, Cindy Simpson, Rajanikanth Vadigepalli, Sylvie Memet, Igor Dozmorov, and Marcia R. Saban

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Gangliocytic paraganglioma: case report and review of the literature, Agnes Witkiewicz, Avi Galler, and Charles Yeo

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Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice., Hongxia Zhou, Björn H Falkenburger, Jörg B Schulz, Kim Tieu, Zuoshang Xu, and Xu Gang Xia

Manuscripts from 2006

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Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis, Lokesh Agrawal, Jean-Pierre Louboutin, Beverly A.S. Reyes, Elisabeth J. Van Bockstaele, and David S. Strayer

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Scientific issues related to the cytology proficiency testing regulations, George Birdsong, Lydia Howell, Karen Atkinson, R. Marshall Austin, Marluce Bibbo, Thomas A. Bonfiglio, Diane D. Davey, Catherine Keebler, Dina Mody, Lynnette Savaloja, Jacalyn Papillo, Marianne Prey, Stephen Raab, Brenda L. Schultz, and Diane Solomon

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Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains, Nikolay M. Borisov, Nick I. Markevitch, Jan B. Hoek, and Boris N. Kholodenko

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A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks, Holger Conzelmann; Julio Saez-Rodriguez; Thomas Sauter; Boris N. Kholodenko PhD, DSci; and Ernst D. Gilles

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Structural and functional features and significance of the physical linkage between ER and mitochondria., György Csordás, Christian Renken, Péter Várnai, Ludivine Walter, David Weaver, Karolyn F Buttle, Tamás Balla, Carmen A Mannella, and György Hajnóczky

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SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells., Giancarlo Ghiselli

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The molecular portraits of breast tumors are conserved acress microarray platforms, Zhiyuan Hu, Cheng Fan, Daniel S. Oh, J. S. Marron, Xiaping He, Bahjat F. Qaqish, Chad Livasy, Lisa A. Carey, Evangeline Reynolds, Lynn Dressler, Andrew Nobel, Joel Parker, Matthew G. Ewend, Lynda R. Sawyer, Junyuan Wu, Yudong Liu, Rita Nanda, Maria Tretiakova, Alejandra Ruiz Orrico, Donna Dreher, Juan P. Palazzo, Laurent Perreard, Edward Nelson, Mary Mone, Heidi Hansen, Michael Mullins, John F. Quackenbush, Matthew J. Ellis, Olufunmilayo I. Olopade, Philip S. Bernard, and Charles M. Perou

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Chronic-alcohol exposure alters IGF1 signaling in H9c2 cells via changes in PKC delta, Richard Ila and Michele Solem

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Combined effects of aldehyde dehydrogenase variants and maternal mitochondrial genes on alcohol consumption, Yedy Israel, Maria E. Quintanilla, Amalia Sapag, and Lutske Tampier

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A universal reference sample derived from clone vector for improved detection of differential gene expression, Rishi L. Khan, Gregory E. Gonye, Guang Gao, and James S. Schwaber

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Cell-signalling dynamics in time and space, Boris N. Kholodenko PhD, DSci

Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades, Nick I. Markevich; Mikhail A. Tsyganov; Jan B. Hoek; and Boris N. Kholodenko PhD, DSci

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Mixed germ cell sex cord-stromal tumors of the testis and ovary. Morphological, immunohistochemical, and molecular genetic study of seven cases, Michal Michal, Tomas Vanacek, Radek Sima, Petr Mukensnabl, Ondrej Hes, Dmitry V. Kazakov, Jozef Matoska, Anna Zuntova, Vladimir Dvorak, and Alexander Talerman

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Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay., Laurent Perreard, Cheng Fan, John F Quackenbush, Michael Mullins, Nicholas P Gauthier, Edward Nelson, Mary Mone, Heidi Hansen, Saundra S Buys, Karen Rasmussen, Alejandra Ruiz Orrico, Donna Dreher, Rhonda Walters, Joel Parker, Zhiyuan Hu, Xiaping He, Juan P Palazzo, Olufunmilayo I Olopade, Aniko Szabo, Charles M Perou, and Philip S Bernard

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The inflammatory and normal transcriptome of mouse bladder detrusor and mucosa, Marcia R. Saban, Helen L. Hellmich, Mary Turner, Ngoc-Bich Nguyen, Rajanikanth Vadigepalli, David W. Dyer, Robert E. Hurst, Michael Centola, and Ricardo Saban

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No vaccine against HIV yet--are we not perfectly equipped?, Mahender Singh

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Voltage-dependent gating rearrangements in the intracellular T1-T1 interface of a K+ channel., Guangyu Wang and Manuel Covarrubias

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Quantifying gene network connectivity in silico: Scalability and accuracy of a modular approach, Nirupama Yalamanchili, Daniel E. Zak, Babatunde A. Ogunnaike, James S. Schwaber, Andres Kriete, and Boris N. Kholodenko

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Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling, Daniel E. Zak, Haiping Hao, Rajanikanth Vadigepalli, Gregory M. Miller, Babatunde A. Ogunnaike, and James S. Schwaber

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Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling, Daniel E. Zak, Haiping Hao, Rajanikanth Vadigepalli, Gregory M. Miller, Babatunde A. Ogunnaike, and James S. Schwaber

Manuscripts from 2005

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Palm is expressed in both developing and adult mouse lens and retina., Meryl Castellini, Louise V Wolf, Bharesh K Chauhan, Deni S Galileo, Manfred W Kilimann, Ales Cvekl, and Melinda K Duncan

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D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafish., Giancarlo Ghiselli and Steven A Farber

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Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis., Muniswamy Madesh, Brian J Hawkins, Tatyana Milovanova, Cunnigaiper D Bhanumathy, Suresh K Joseph, Satish P Ramachandrarao, Kumar Sharma, Tomohiro Kurosaki, and Aron B Fisher

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Hinderin, a five-domains protein including coiled-coil motifs that binds to SMC3., Chirag A Patel and Giancarlo Ghiselli

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Two-dimensional Fluorescence Difference Gel Electrophoresis Analysis of the Urine Proteome in Human Diabetic Nephropathy, Kumar Sharma, SoHee Lee, Steven Han, Sungchun Lee, Barbara Francos, Peter McCue, Richard Wassell, M. Alexander Shaw, and Satish P. RamachandraRao

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The use of time-resolved fluorescence imaging in the study of protein kinase C localisation in cells., Christopher D Stubbs, Stanley W Botchway, Simon J Slater, and Anthony W Parker

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Multiple Metabolic Hits Converge on CD36 as Novel Mediator of Tubular Epithelial Apoptosis in Diabetic Nephropathy, Katalin Susztack, Emilio Ciccone, Peter McCue, Kumar Sharma, and Erwin Böttinger

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Functionally active t1-t1 interfaces revealed by the accessibility of intracellular thiolate groups in kv4 channels., Guangyu Wang, Mohammad Shahidullah, Carmen A Rocha, Candace Strang, Paul J Pfaffinger, and Manuel Covarrubias

Manuscripts from 2004

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Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin., Gregory Bix, Jian Fu, Eva M Gonzalez, Laura Macro, Amy Barker, Shelly Campbell, Mary M Zutter, Samuel A Santoro, Jiyeun K Kim, Magnus Höök, Charles C Reed, and Renato V Iozzo

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Biochemical enrichment and biophysical characterization of a taste receptor for L-arginine from the catfish, Ictalurus puntatus., William Grosvenor, Yuri Kaulin, Andrew I Spielman, Douglas L Bayley, D Lynn Kalinoski, John H Teeter, and Joseph G Brand

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Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades., Nick I Markevich, Jan B. Hoek, and Boris N. Kholodenko

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Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15., Hayley J McKee, Patricia Y T'sao, Maria Vera, Puri Fortes, and David S Strayer

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Characterization of the chicken inward rectifier K+ channel IRK1/Kir2.1 gene., Hideki Mutai, Lawrence C Kenyon, Emily Locke, Nami Kikuchi, and John Carl Oberholtzer

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Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit., Muqing Yi, David Weaver, and György Hajnóczky

Manuscripts from 2003

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Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema., Dong Kwan Kim, Jianliang Zhu, Benjamin W Kozyak, James M Burkman, Neal A Rubinstein, Edward B Lankford, Hansell H Stedman, Taitan Nguyen, Sanford Levine, and Joseph B Shrager

Manuscripts from 2002

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Stretch-induced calcium release in smooth muscle., Guangju Ji, Robert J Barsotti, Morris E Feldman, and Michael I Kotlikoff

Manuscripts from 2001

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Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol., E Garver, Tu Gc, Q N Cao, M Aini, F Zhou, and Y Israel

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Acidification-induced sensitization to thermoradiotherapy in breast cancer, Dennis B. Leeper and L T. Komarnicky

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VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release., M Madesh and György Hajnóczky

Manuscripts from 2000

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Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons., Y Ezura, S Chakravarti, A Oldberg, I Chervoneva, and D E Birk

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Distance Learning Programs for Pathology Education, Bruce Fenderson and Anthony J. Frisby

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Single-channel properties in endoplasmic reticulum membrane of recombinant type 3 inositol trisphosphate receptor., D O Mak, S McBride, V Raghuram, Y Yue, Suresh K. Joseph, and J K Foskett

Documents from 1997

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Using World-Wide-Web technology for pathology education, Anthony J. Frisby, Bruce Fenderson, Christopher D. Braster, and Rodney B. Murray

Manuscripts from 1994

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Mechanisms of cell injury by activated oxygen species., John L. Farber

Manuscripts from 1990

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The role of calcium ions in toxic cell injury., John L. Farber