Chordoma is a rare but locally aggressive malignant neoplasm showing notochordal differentiation. The clinical differential diagnoses can be extensive, and definitive diagnosis often relies on histopathologic evaluation. Histologically, chordoma shows dual epithelial and mesenchymal differentiation, with various morphologies. Despite surgical resection and use of adjuvant radiation therapy, the local recurrence rate of chordoma remains high. We aim to establish factors associated with the increased risk of recurrence and help guide treatment decisions.
Recommended CitationAbraham, MD, John A. and Jiang, MD, PhD, Wei, "Assessment for Risk Factors Associated with Local Recurrence in Chordoma" (2015). Department of Pathology, Anatomy and Cell Biology Faculty Papers. Paper 159.