Title

Epigenetic Approaches to Epithelial Ovarian Cancer

Document Type

Presentation

Presentation Date

4-12-2017

Abstract

Outline:

Therapeutic targeting ARID1A mutation in ovarian cancer (Clear Cell and Endometrioid).

  • Synthetic lethality with ARID1A mutation
  • Targeting mutual exclusivity between ARID1A and TP53 mutations

Overcoming platinum resistance using BET inhibitors (High-grade Serous).

Presentation: 52:04