Article Title

Clozapine, Fluoxetine, and Benztropine- associated Ileus: Case Report

Authors

Pegah Pajouhi M.D. (PGY1), Stanford UniversityFollow
James A. Bourgeois O.D., M.D., University of California, DavisFollow

Abstract

Gastrointestinal complications of anticholinergic medications are prevalent, potentially life-threatening, and could be more actively prevented. We present a case report of an ileus that required surgical intervention and developed in the context of clozapine, benztropine, and fluoxetine use. The case exemplifies the potential anticholinergic toxicities of clozapine and benztropine as well as possible pharmacokinetic interactions between fluoxetine, clozapine, and benztropine. We discuss ways to minimize the likelihood of anticholinergic complications with these medications.

Recommended Citation

Pajouhi, Pegah M.D. (PGY1) and Bourgeois, James A. O.D., M.D. (2007) "Clozapine, Fluoxetine, and Benztropine- associated Ileus: Case Report," Jefferson Journal of Psychiatry: Vol. 21: Iss. 1, Article 1.
DOI: https://doi.org/10.29046/JJP.021.1.001
Available at: https://jdc.jefferson.edu/jeffjpsychiatry/vol21/iss1/1