https://doi.org/10.29046/JJP.012.2.002">
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Jefferson Journal of Psychiatry

Abstract

Patients with schizophrenia are typically treated with a neuroleptic and some form of psychosocial intervention. In spite of optimum treatment, up to one-third of patients continue to remain severely disabled due to persistent positive or negative symptoms. A variety of drugs have been tried as alternatives or additions to traditional neuroleptics in these patients. This paper is a review of these nonneuroleptic treatment alternatives and an attempt to establish some guidelines for their use.

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https://doi.org/10.29046/JJP.012.2.002">