Patients with schizophrenia are typically treated with a neuroleptic and some form of psychosocial intervention. In spite of optimum treatment, up to one-third of patients continue to remain severely disabled due to persistent positive or negative symptoms. A variety of drugs have been tried as alternatives or additions to traditional neuroleptics in these patients. This paper is a review of these nonneuroleptic treatment alternatives and an attempt to establish some guidelines for their use.
John, MD, Sajiv and Mahableshwarkar, MD, Atul
"Non-Neuroleptic Pharmacotherapy of Schizophrenia,"
Jefferson Journal of Psychiatry: Vol. 12
, Article 6.
Available at: http://jdc.jefferson.edu/jeffjpsychiatry/vol12/iss2/6