Complete resolution of gastric amyloidosis after autologous stem cell transplantation.

Authors

Dinu Cherian, Jefferson Medical College
Kristin Braun, Thomas Jefferson University
Neal Flomenberg, Thomas Jefferson UniversityFollow
Juan P. Palazzo, Thomas Jefferson UniversityFollow
David Kastenberg, Thomas Jefferson UniversityFollow

Document Type

Article

Publication Date

9-1-2008

Comments

This article has been peer reviewed. It is the authors' final version prior to publication in Endoscopy

Volume 40, Suppl 2, September 2008, Pages E167-168

The published version is available at DOI: 10.1055/s-2007-995793. Copyright © Thieme Medical Publishers Inc.

Abstract

A 48-year-old female with multiple myeloma (MM) and amyloidosis presented with massive upper gastrointestinal (GI) bleeding one week after autologous stem cell transplantation (autologous-SCT). Esophagogastroduodenoscopy (EGD) demonstrated necrotic, purple, pigmented, friable lesions throughout the stomach (Figure 1a), along with a bleeding ulcer in the cardia (Figure 1b, Video 1) which was successfully treated with epinephrine (1:10,000) injections. Biopsies demonstrated nodular amyloid deposition (Figures 2) which was Congo red positive. The patient had no further hematemesis and was discharged home 4 days later. Ten months after autologous-SCT, EGD revealed a normal stomach (Figure 3, Video 2) with no histologic evidence of amyloid.

Recommended Citation

Cherian, Dinu; Braun, Kristin; Flomenberg, Neal; Palazzo, Juan P.; and Kastenberg, David, "Complete resolution of gastric amyloidosis after autologous stem cell transplantation." (2008). Division of Gastroenterology and Hepatology Faculty Papers. Paper 7.
https://jdc.jefferson.edu/gastro_hepfp/7

PubMed ID

18668456